Structures and general transport mechanisms by the major facilitator superfamily (MFS)

D Drew, RA North, K Nagarathinam… - Chemical reviews, 2021 - ACS Publications
The major facilitator superfamily (MFS) is the largest known superfamily of secondary active
transporters. MFS transporters are responsible for transporting a broad spectrum of …

Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria

I Alav, J Kobylka, MS Kuth, KM Pos, M Picard… - Chemical …, 2021 - ACS Publications
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Organic cation transporters in health and disease

H Koepsell, LC Daws - Pharmacological reviews, 2020 - Elsevier
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

Crystal structure of the human glucose transporter GLUT1

D Deng, C Xu, P Sun, J Wu, C Yan, M Hu, N Yan - Nature, 2014 - nature.com
The glucose transporter GLUT1 catalyses facilitative diffusion of glucose into erythrocytes
and is responsible for glucose supply to the brain and other organs. Dysfunctional mutations …

Shared molecular mechanisms of membrane transporters

D Drew, O Boudker - Annual review of biochemistry, 2016 - annualreviews.org
The determination of the crystal structures of small-molecule transporters has shed light on
the conformational changes that take place during structural isomerization from outward-to …

Structural biology of the major facilitator superfamily transporters

N Yan - Annual review of biophysics, 2015 - annualreviews.org
The ancient and ubiquitous major facilitator superfamily (MFS) represents the largest
secondary transporter family and plays a crucial role in a multitude of physiological …

Major facilitator superfamily

SS Pao, IT Paulsen, MH Saier Jr - Microbiology and molecular …, 1998 - Am Soc Microbiol
The major facilitator superfamily (MFS) is one of the two largest families of membrane
transporters found on Earth. It is present ubiquitously in bacteria, archaea, and eukarya and …

Crystal structure of a bacterial homologue of glucose transporters GLUT1–4

L Sun, X Zeng, C Yan, X Sun, X Gong, Y Rao, N Yan - Nature, 2012 - nature.com
Glucose transporters are essential for metabolism of glucose in cells of diverse organisms
from microbes to humans, exemplified by the disease-related human proteins GLUT1, 2, 3 …

[LLIBRE][B] Biomembranes: molecular structure and function

RB Gennis - 2013 - books.google.com
New textbooks at all levels of chemistry appear with great regularity. Some fields like basic
biochemistry, organic reaction mechanisms, and chemical thermody namics are well …

Facilitative glucose transporters

M Mueckler - European journal of biochemistry, 1994 - Wiley Online Library
Facilitative glucose transport is mediated by members of the Glut protein family that belong
to a much larger superfamily of 12 transmembrane segment transporters. Six members of …