The value of existing regulatory frameworks for the environmental risk assessment of agricultural pest control using gene drives

J Romeis, J Collatz, DCM Glandorf… - Environmental Science & …, 2020 - Elsevier
The application of (synthetic) gene drives is a powerful tool to control populations of insects
that are agricultural pests, vectors of diseases, or a threat to biodiversity potentially leading …

Potential use of gene drive modified insects against disease vectors, agricultural pests and invasive species poses new challenges for risk assessment

Y Devos, JD Mumford, MB Bonsall… - Critical Reviews in …, 2022 - Taylor & Francis
Potential future application of engineered gene drives (GDs), which bias their own
inheritance and can spread genetic modifications in wild target populations, has sparked …

Roads forward for European GMO Policy—Uncertainties in wake of ECJ judgment have to be mitigated by regulatory reform

M Wasmer - Frontiers in Bioengineering and Biotechnology, 2019 - frontiersin.org
This article gives an overview of legal and procedural uncertainties regarding genome
edited organisms and possible ways forward for European GMO policy. After a recent …

A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context

J Kuzma, F Gould, Z Brown, J Collins… - Journal of …, 2018 - Taylor & Francis
The deployment of gene drives is emerging as an alternative for protecting endangered
species, controlling agricultural pests, and reducing vector-borne diseases. This paper …

Adequacy and sufficiency evaluation of existing EFSA guidelines for the molecular characterisation, environmental risk assessment and post‐market environmental …

EFSA Panel on Genetically Modified Organisms … - Efsa …, 2020 - Wiley Online Library
Advances in molecular and synthetic biology are enabling the engineering of gene drives in
insects for disease vector/pest control. Engineered gene drives (that bias their own …

Are market GM plants an unrecognized platform for bioterrorism and biocrime?

S Mueller - Frontiers in bioengineering and biotechnology, 2019 - frontiersin.org
This article discusses a previously unrecognized avenue for bioterrorism and biocrime. It is
suggested that new gene editing technologies may have the potential to create plants that …

Lessons learned from the introduction of genetically engineered crops: relevance to gene drive deployment in Africa

H Quemada - Transgenic Research, 2022 - Springer
The application of gene drives to achieve public health goals, such as the suppression of
Anopheles gambiae populations, or altering their ability to sustain Plasmodium spp …

Improving risk governance strategies via learning: a comparative analysis of solar radiation modification and gene drives

K Grieger, JB Wiener, J Kuzma - Environment Systems and Decisions, 2024 - Springer
Stratospheric aerosol injection (SAI) and gene drive organisms (GDOs) have been proposed
as technological responses to complex entrenched environmental challenges. They also …

dc transport in superconducting point contacts: A full-counting-statistics view

JC Cuevas, W Belzig - Physical Review B—Condensed Matter and Materials …, 2004 - APS
We present a comprehensive theoretical analysis of the dc transport properties of
superconducting point contacts. We determine the full-counting statistics for these junctions …

CRISPR‐based gene drive in agriculture will face technical and governance challenges

N Gutzmann, JE Elsensohn, JC Barnes, J Baltzegar… - EMBO …, 2017 - embopress.org
Courtier-Orgogozo et al [1] recently called for public debate about the use of CRISPR-based
gene drive (GD) in agricultural pest management. We agree that this use of GD deserves …