CRISPR/Cas9 therapeutics: progress and prospects

T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - Signal transduction and …, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …

[HTML][HTML] CRISPR/Cas9 landscape: current state and future perspectives

M Tyumentseva, A Tyumentsev, V Akimkin - International journal of …, 2023 - mdpi.com
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 is a unique
genome editing tool that can be easily used in a wide range of applications, including …

Current advancement in the application of prime editing

Z Huang, G Liu - Frontiers in Bioengineering and Biotechnology, 2023 - frontiersin.org
Prime editing (PE) is a precise genome manipulation technology based on the “search and
replace” approach of the CRISPR-Cas9 system, while it does not require the exogenous …

Synonymous edits in the Escherichia coli genome have substantial and condition-dependent effects on fitness

DD Yang, LM Rusch, KA Widney… - Proceedings of the …, 2024 - pnas.org
CRISPR-Cas-based genome editing is widely used in bacteria at scales ranging from
construction of individual mutants to massively parallel libraries. This procedure relies on …

Generation of human isogenic induced pluripotent stem cell lines with CRISPR prime editing

LL Bonnycastle, AJ Swift, EC Mansell, A Lee… - The CRISPR …, 2024 - liebertpub.com
We developed an efficient CRISPR prime editing protocol and generated isogenic-induced
pluripotent stem cell (iPSC) lines carrying heterozygous or homozygous alleles for putatively …

Green revolution to genome revolution: driving better resilient crops against environmental instability

R Chawla, A Poonia, K Samantara… - Frontiers in …, 2023 - frontiersin.org
Crop improvement programmes began with traditional breeding practices since the
inception of agriculture. Farmers and plant breeders continue to use these strategies for crop …

CRISPR/CAS9: a promising approach for the research and treatment of cardiovascular diseases

M Dong, J Liu, C Liu, H Wang, W Sun, B Liu - Pharmacological Research, 2022 - Elsevier
The development of gene-editing technology has been one of the biggest advances in
biomedicine over the past two decades. Not only can it be used as a research tool to build a …

Photo‐Controllable Smart Hydrogels for Biomedical Application: A Review

Y Zhao, B Ran, D Lee, J Liao - Small Methods, 2024 - Wiley Online Library
Nowadays, smart hydrogels are being widely studied by researchers because of their
advantages such as simple preparation, stable performance, response to external stimuli …

Gene-Based Developments in Improving Quality of Tomato: Focus on Firmness, Shelf Life, and Pre-and Post-Harvest Stress Adaptations

H Nie, X Yang, S Zheng, L Hou - Horticulturae, 2024 - mdpi.com
Tomato (Solanum lycopersicum) is a widely consumed vegetable crop with significant
economic and nutritional importance. This review paper discusses the recent advancements …

[HTML][HTML] Navigating the CRISPR/Cas Landscape for Enhanced Diagnosis and Treatment of Wilson's Disease

W Choi, S Cha, K Kim - Cells, 2024 - mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-
associated protein (Cas) system continues to evolve, thereby enabling more precise …