Entropically driven binding of Camptothecin in the minor groove of salmon testes DNA

S Yanthan, V Rupreo, J Bhattacharyya - International Journal of Biological …, 2024 - Elsevier
The present study focuses on binding association of Camptothecin (CMT) towards natural
deoxy-ribonucleic acid (salmon testes, ST) under physiological conditions of pH 7.4 …

Mechanistic investigation into the binding property of Yohimbe towards natural polymeric DNAs

S Luikham, S Yanthan, J Bhattacharyya - Scientific Reports, 2023 - nature.com
DNA interactions with multivalent ligand (s) have increasingly become the subject of
substantial research. For several small molecules with therapeutic potential, nucleic acids …

Structural insight into groove binding of yohimbine with calf thymus DNA: A spectroscopic, calorimetric, and computational approach

S Luikham, A Mavani, D Sinha… - The Journal of Physical …, 2023 - ACS Publications
A variety of anticancer and antibacterial drugs target DNA as one of their primary
intracellular targets. Understanding ligand–DNA interactions and develo** new …

An insight for the interaction of Aceclofenac with hemoglobin using spectroscopic, electrochemical and in silico approaches

S Yadav, MB Singh, S Sewariya, SB Yadav… - Discover …, 2024 - Springer
The interactions between protein and ligand are crucial to practically every biological
function in the body, and investigations of these interactions are critical from the perspective …