Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide
cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent …

For at least two hundred years, Neisseria meningitidis (the meningococcus), the cause of
epidemic meningitis and sepsis, has inflicted rapid death, disability and fear on disparate …

The different sialic acid (serogroups B, C, Y, and W-135) and nonsialic acid (serogroup A)
capsular polysaccharides expressed by Neisseria meningitidis are major virulence factors …

Lipopolysaccharide (LPS), also known as endotoxin due to its severe pathophysiological
effects in infected subjects, is an essential component of the outer membrane (OM) of most …

The distribution of serogroups and multilocus sequence types (STs) in collections of disease-
associated and carried meningococci from the period 1991 to 2000 in three European …

Background Neisseria meningitidis is a diverse commensal bacterium that occasionally
causes severe invasive disease. The relationship between meningococcal genotype and …

Polysialic acid is a unique cell surface polysaccharide found in the capsule of neuroinvasive
bacteria and as a highly regulated post-translational modification of the neural cell adhesion …

The exclusive human pathogen Neisseria meningitidis expresses lipooligosaccharide
(LOS), an endotoxin that is structurally distinct from the lipopolysaccharides (LPS) of enteric …

The molecular basis for the resistance of serogroup B Neisseria meningitidis to the
bactericidal activity of normal human sera (NHS) was examined with a NHS-resistant …

A survey of Haemophilus influenzae strains indicated that around one‐third of capsular
strains and over two‐thirds of non‐typeable strains included sialic acid in their …