NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

Quantitative serum nuclear magnetic resonance metabolomics in large-scale epidemiology: a primer on-omic technologies

P Würtz, AJ Kangas, P Soininen… - American journal of …, 2017 - academic.oup.com
Detailed metabolic profiling in large-scale epidemiologic studies has uncovered novel
biomarkers for cardiometabolic diseases and clarified the molecular associations of …

Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics

P Soininen, AJ Kangas, P Würtz, T Suna… - Circulation …, 2015 - Am Heart Assoc
Metabolomics is becoming common in epidemiology due to recent developments in
quantitative profiling technologies and appealing results from their applications for …

NMR and pattern recognition methods in metabolomics: from data acquisition to biomarker discovery: a review

A Smolinska, L Blanchet, LMC Buydens… - Analytica chimica …, 2012 - Elsevier
Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

P Soininen, AJ Kangas, P Würtz, T Tukiainen… - Analyst, 2009 - pubs.rsc.org
A high-throughput proton (1H) nuclear magnetic resonance (NMR) metabonomics approach
is introduced to characterise systemic metabolic phenotypes. The methodology combines …

Chemometrics in metabolomics—a review in human disease diagnosis

R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with develo** methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …

Clinical lipidomics: realizing the potential of lipid profiling

TG Meikle, K Huynh, C Giles, PJ Meikle - Journal of lipid research, 2021 - ASBMB
Dysregulation of lipid metabolism plays a major role in the etiology and sequelae of
inflammatory disorders, cardiometabolic and neurological diseases, and several forms of …

Metabolic signatures of insulin resistance in 7,098 young adults

P Würtz, VP Mäkinen, P Soininen, AJ Kangas… - Diabetes, 2012 - Am Diabetes Assoc
Metabolite associations with insulin resistance were studied in 7,098 young Finns (age 31±3
years; 52% women) to elucidate underlying metabolic pathways. Insulin resistance was …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Long-term leisure-time physical activity and serum metabolome

UM Kujala, VP Mäkinen, I Heinonen, P Soininen… - Circulation, 2013 - Am Heart Assoc
Background—Long-term physical inactivity seems to cause many health problems. We
studied whether persistent physical activity compared with inactivity has a global effect on …