The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

There are few medications with demonstrated efficacy for the treatment of posttraumatic
stress disorder (PTSD). Treatment guidelines have unequivocally designated psychotherapy …

Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

The generalization of fear memories is an adaptive neurobiological process that promotes
survival in complex and dynamic environments. When confronted with a potential threat, an …

The type 2 cannabinoid receptor (CB2R) was initially regarded as a peripheral cannabinoid
receptor. However, recent technological advances in gene detection, alongside the …

Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating
conditions linked to oxidative stress and neurodegeneration. When available, the …

Cocaine abuse continues to be a serious health problem worldwide. Despite intense
research there is currently no FDA-approved medication to treat cocaine use disorder. The …

Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

Depression is characterized by continuous low mood and loss of interest or pleasure in
enjoyable activities. First-line medications for mood disorders mostly target the …

Cannabis is one of the oldest crops grown, traditionally held religious attachments in various
cultures for its medicinal use much before its introduction to Western medicine. Multiple …