The role of iron in brain ageing and neurodegenerative disorders
In the CNS, iron in several proteins is involved in many important processes such as oxygen
transportation, oxidative phosphorylation, myelin production, and the synthesis and …
transportation, oxidative phosphorylation, myelin production, and the synthesis and …
Quantitative susceptibility map** (QSM): decoding MRI data for a tissue magnetic biomarker
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …
chemical shift for observer protons within the molecule and a magnetic susceptibility …
[HTML][HTML] Ageing and Parkinson's disease: why is advancing age the biggest risk factor?
As the second most common age related neurodegenerative disease after Alzheimer's
disease, the health, social and economic impact resulting from Parkinson's disease will …
disease, the health, social and economic impact resulting from Parkinson's disease will …
Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration
Perturbations in iron homeostasis and iron accumulation feature in several
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …
On cell loss and selective vulnerability of neuronal populations in Parkinson's disease
Significant advances have been made uncovering the factors that render neurons
vulnerable in Parkinson's disease (PD). However, the critical pathogenic events leading to …
vulnerable in Parkinson's disease (PD). However, the critical pathogenic events leading to …
Iron neurochemistry in Alzheimer's disease and Parkinson's disease: targets for therapeutics
Brain iron homeostasis is increasingly recognized as a potential target for the development
of drug therapies for aging‐related disorders. Dysregulation of iron metabolism associated …
of drug therapies for aging‐related disorders. Dysregulation of iron metabolism associated …
[HTML][HTML] Quantitative susceptibility map** (QSM) as a means to measure brain iron? A post mortem validation study
Quantitative susceptibility map** (QSM) is a novel technique which allows determining the
bulk magnetic susceptibility distribution of tissue in vivo from gradient echo magnetic …
bulk magnetic susceptibility distribution of tissue in vivo from gradient echo magnetic …
Susceptibility‐weighted imaging and quantitative susceptibility map** in the brain
Susceptibility‐weighted imaging (SWI) is a magnetic resonance imaging (MRI) technique
that enhances image contrast by using the susceptibility differences between tissues. It is …
that enhances image contrast by using the susceptibility differences between tissues. It is …
Eriodictyol ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via vitamin D receptor-mediated Nrf2 activation
Background Alzheimer's disease (AD) is the most common type of neurodegenerative
disease in the contemporary era, and it is still clinically incurable. Eriodictyol, a natural …
disease in the contemporary era, and it is still clinically incurable. Eriodictyol, a natural …
Overview of quantitative susceptibility map**
Magnetic susceptibility describes the magnetizability of a material to an applied magnetic
field and represents an important parameter in the field of MRI. With the recently introduced …
field and represents an important parameter in the field of MRI. With the recently introduced …