Bacterial genome instability

E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - journals.asm.org
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …

Bacteriophages of the Order Crassvirales: What Do We Currently Know about This Keystone Component of the Human Gut Virome?

L Smith, E Goldobina, B Govi, AN Shkoporov - Biomolecules, 2023 - mdpi.com
The order Crassvirales comprises dsDNA bacteriophages infecting bacteria in the phylum
Bacteroidetes that are found in a variety of environments but are especially prevalent in the …

Analysis of metagenome-assembled viral genomes from the human gut reveals diverse putative CrAss-like phages with unique genomic features

N Yutin, S Benler, SA Shmakov, YI Wolf… - Nature …, 2021 - nature.com
CrAssphage is the most abundant human-associated virus and the founding member of a
large group of bacteriophages, discovered in animal-associated and environmental …

[HTML][HTML] Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

EV Koonin, P Starokadomskyy - Studies in history and philosophy of …, 2016 - Elsevier
The question whether or not “viruses are alive” has caused considerable debate over many
years. Yet, the question is effectively without substance because the answer depends …

Viruses and mobile elements as drivers of evolutionary transitions

EV Koonin - … Transactions of the Royal Society B …, 2016 - royalsocietypublishing.org
The history of life is punctuated by evolutionary transitions which engender emergence of
new levels of biological organization that involves selection acting at increasingly complex …

A survey of transposable element classification systems–a call for a fundamental update to meet the challenge of their diversity and complexity

B Piégu, S Bire, P Arensburger, Y Bigot - Molecular phylogenetics and …, 2015 - Elsevier
The increase of publicly available sequencing data has allowed for rapid progress in our
understanding of genome composition. As new information becomes available we should …

An intron endonuclease facilitates interference competition between coinfecting viruses

EA Birkholz, CJ Morgan, TG Laughlin, RK Lau… - Science, 2024 - science.org
Introns containing homing endonucleases are widespread in nature and have long been
assumed to be selfish elements that provide no benefit to the host organism. These genetic …

Homing endonucleases: DNA scissors on a mission

M Hafez, G Hausner - Genome, 2012 - cdnsciencepub.com
Buried within the genomes of many microorganisms are genetic elements that encode rare-
cutting homing endonucleases that assist in the mobility of the elements that encode them …

The coevolution of fungal mitochondrial introns and their homing endonucleases (GIY-YIG and LAGLIDADG)

AH Megarioti, VN Kouvelis - Genome biology and evolution, 2020 - academic.oup.com
Fungal mitochondrial (mt) genomes exhibit great diversity in size which is partially attributed
to their variable intergenic regions and most importantly to the inclusion of introns within …

[HTML][HTML] Organellar introns in fungi, algae, and plants

J Mukhopadhyay, G Hausner - Cells, 2021 - mdpi.com
Introns are ubiquitous in eukaryotic genomes and have long been considered as 'junk
RNA'but the huge energy expenditure in their transcription, removal, and degradation …