In addition to malignant neoplastic cells, cancer tissues also include immune cells,
fibroblasts, and endothelial cells, including an abundant collection of growth factors …

Complex interactions between tumor and host cells regulate systemic tumor dissemination,
a process that begins early at the primary tumor site and goes on until tumor cells detach …

Breast cancer affects one in eight women in their lifetime. Though diet, age and genetic
predisposition are established risk factors, the majority of breast cancers have unknown …

NKT cells are an unusual population of T cells recognizing lipids presented by CD1d, a non-
classical class-I-like molecule, rather than peptides presented by conventional MHC …

NKT cells are a relatively newly recognized member of the immune community, with
profound effects on the rest of the immune system despite their small numbers. They are true …

Improved hygiene has been suggested to influence certain autoimmune disorders, such as
multiple sclerosis. In this study, we addressed whether altering the composition of gut flora …

Natural killer T (NKT) cells are innate-like lymphocytes that generally recognize lipid
antigens and are enriched in microvascular compartments of the liver. NKT cells can be …

The MHC fold is found in proteins that have a range of functions in the maintenance of an
organism's health, from immune regulation to fat metabolism. Well adapted for antigen …

Mouse models of human cancer have played a vital role in understanding tumorigenesis
and answering experimental questions that other systems cannot address. Advances …

Osteopontin (OPN) is a secreted protein present in bodily fluids and tissues. It is subject to
multiple post‐translational modifications, including phosphorylation, glycosylation …