Aim Breast cancer is the most common cancer among women and one of the most important
causes of death among them. This review aimed to investigate the incidence and mortality …

Over the past decade, the gut microbiota has received considerable attention for its
interactions with the host. Microbial β-glucuronidase generated by this community has …

Background The long time from exposure to potentially harmful chemicals until breast
cancer occurrence poses challenges for designing etiologic studies and for implementing …

Women with dense breasts have an increased lifetime risk of malignancy that has been
attributed to a higher epithelial density. Quantitative proteomics, collagen analysis, and …

Tissue stem-progenitor cell frequency has been implicated in tumor risk and progression,
but tissue-specific factors linking these associations remain ill-defined. We observed that stiff …

Purpose Hormone replacement therapy (HRT) use increases breast cancer risk and
mammographic density (MD). We examine whether MD mediates or modifies the …

Population studies show worrisome trends towards earlier breast development, difficulty in
breastfeeding, and increasing rates of breast cancer in young women. Multiple …

Apelin/APJ is widely distributed in various tissues in the body and participates in the
regulation of physiological and pathological mechanisms such as autophagy, apoptosis …

Mammographic breast density (MBD) has been proven to be an important risk factor for
breast cancer and an important determinant of mammographic screening performance. The …

Estrogens and progesterone control breast development and carcinogenesis via their
cognate receptors expressed in a subset of luminal cells in the mammary epithelium. How …