A review of phospholipid encapsulated ultrasound contrast agent microbubble physics
B Helfield - Ultrasound in medicine & biology, 2019 - Elsevier
Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …
from anatomic imaging to the assessment of microvascular blood flow characteristics and …
20 years of ultrasound contrast agent modeling
The merits of ultrasound contrast agents (UCAs) were already known in the 1960s. It was,
however, not until the 1990s that UCAs were clinically approved and marketed. In these …
however, not until the 1990s that UCAs were clinically approved and marketed. In these …
[HTML][HTML] The influence of inter-bubble spacing on the resonance response of ultrasound contrast agent microbubbles
Ultrasound-driven microbubbles, typically between 1 and 8 µm in diameter, are resonant
scatterers that are employed as diagnostic contrast agents and emerging as potentiators of …
scatterers that are employed as diagnostic contrast agents and emerging as potentiators of …
Evaluating the safety profile of focused ultrasound and microbubble-mediated treatments to increase blood-brain barrier permeability
Introduction: Treatment of several diseases of the brain are complicated by the presence of
the skull and the blood-brain barrier (BBB). Focused ultrasound (FUS) and microbubble …
the skull and the blood-brain barrier (BBB). Focused ultrasound (FUS) and microbubble …
Characterization of contrast agent microbubbles for ultrasound imaging and therapy research
The high efficiency with which gas microbubbles can scatter ultrasound compared with the
surrounding blood pool or tissues has led to their widespread employment as contrast …
surrounding blood pool or tissues has led to their widespread employment as contrast …
Lipid shedding from single oscillating microbubbles
Lipid-coated microbubbles are used clinically as contrast agents for ultrasound imaging and
are being developed for a variety of therapeutic applications. The lipid encapsulation and …
are being developed for a variety of therapeutic applications. The lipid encapsulation and …
Nonlinear resonance behavior and linear shell estimates for Definity™ and MicroMarker™ assessed with acoustic microbubble spectroscopy
There is a growing interest in microbubble based ultrasound contrast imaging applications
in the 5–15 MHz range. In this study, individual microbubbles were insonified at low …
in the 5–15 MHz range. In this study, individual microbubbles were insonified at low …
Experimental and numerical evidence of intensified non-linearity at the microscale: The lipid coated acoustic bubble
A lipid coated bubble (LCB) oscillator is a very interesting non-smooth oscillator with many
important applications ranging from industry and chemistry to medicine. However, due to the …
important applications ranging from industry and chemistry to medicine. However, due to the …
Targeted ultrasound contrast agents for ultrasound molecular imaging and therapy
Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …
Non-linear response and viscoelastic properties of lipid-coated microbubbles: DSPC versus DPPC
For successful in vivo contrast-enhanced ultrasound imaging (CEUS) and ultrasound
molecular imaging, detailed knowledge of stability and acoustical properties of the …
molecular imaging, detailed knowledge of stability and acoustical properties of the …