Circular RNAs (circRNAs) are highly expressed in the central nervous system and are
involved in the regulation of physiological and pathophysiological processes. However, the …

Immunity in a naïve organism is tightly controlled. Adequate proportions of the many immune
cell subsets must be produced to mount efficient responses to eventual challenges. In …

Over the past decade, microRNA‐142 (miR‐142) is emerging as a major regulator of cell
fate decision in the hematopoietic system. However, miR‐142 is expressed in many other …

Stem cell differentiation is a highly dynamic process involving pervasive changes in gene
expression. The large majority of existing studies has characterized differentiation at the …

Single-cell RNA sequencing (scRNA-seq) provides a leap forward in resolving cellular
diversity and developmental trajectories but fails to comprehensively delineate the spatial …

Abstract Objectives miR-142-5p was noted aberrantly expressed and plays important roles
in different pathophysiological conditions in human. The present study aims to examine the …

As one of leading causes of blindness, diabetic retinopathy (DR) is a progressive
microvascular complication of diabetes mellitus (DM). Despite significant efforts have been …

Previous studies have revealed that miR‑142‑5p serves a critical role in human cancer
progression. However, the biological function of miR‑142‑5p in osteosarcoma (OS) …

During embryogenesis, differentiation of pluripotent cells into somatic cell types depends
both on signaling cues and intrinsic gene expression programs. While the molecular …

Introduction The extracellular deposition of β-amyloid (Aβ) is a pathological hallmark in
Alzheimer's disease (AD), which induces microglial activation in the pathology of AD. The …