BDNF, brain, and regeneration: insights from zebrafish

C Lucini, L D'Angelo, P Cacialli, A Palladino… - International journal of …, 2018 - mdpi.com
Zebrafish (Danio rerio) is a teleost fish widely accepted as a model organism for
neuroscientific studies. The adults show common basic vertebrate brain structures, together …

Pathophysiology linking depression and type 2 diabetes: psychotherapy, physical exercise, and fecal microbiome transplantation as damage control

R Subba, R Sandhir, SP Singh… - European Journal of …, 2021 - Wiley Online Library
Diabetes increases the likelihood of develo** depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …

[HTML][HTML] Effects of microplastic exposure on the early developmental period and circadian rhythm of zebrafish (Danio rerio): A comparative study of polylactic acid and …

J Luan, S Zhang, Y Xu, L Wen, X Feng - Ecotoxicology and Environmental …, 2023 - Elsevier
Polyglycolic acid (PGA) is an emerging biodegradable plastic material. Together with
polylactic acid (PLA), PGA is considered a suitable alternative to conventional plastics and …

High-glucose/high-cholesterol diet in zebrafish evokes diabetic and affective pathogenesis: The role of peripheral and central inflammation, microglia and apoptosis

JJ Wang, YJ Li, K Lai, QM Zhong, KA Demin… - Progress in Neuro …, 2020 - Elsevier
Neuroinflammation and metabolic deficits contribute to the etiology of human affective
disorders, such as anxiety and depression. The zebrafish (Danio rerio) has recently …

[HTML][HTML] Regenerative neurogenesis: the integration of developmental, physiological and immune signals

T Becker, CG Becker - Development, 2022 - journals.biologists.com
In fishes and salamanders, but not mammals, neural stem cells switch back to neurogenesis
after injury. The signalling environment of neural stem cells is strongly altered by the …

Neurotrophin-3 and neurotrophin-4: the unsung heroes that lies behind the meninges

NA Omar, J Kumar, SL Teoh - Neuropeptides, 2022 - Elsevier
Neurotrophin is a growth factor that regulates the development and repair of the nervous
system. From all factors, two pioneer groups, the nerve growth factor (NGF) and brain …

NT-4 attenuates neuroinflammation via TrkB/PI3K/FoxO1 pathway after germinal matrix hemorrhage in neonatal rats

T Wang, J Zhang, P Li, Y Ding, J Tang, G Chen… - Journal of …, 2020 - Springer
Background Neuroinflammation plays an important role in pathogenesis of germinal matrix
hemorrhage (GMH). Neurotrophin-4 (NT-4) is a member of the neurotrophin family and …

Neuroanatomical distribution and functions of brain‐derived neurotrophic factor in zebrafish (Danio rerio) brain

SK Anand, AC Mondal - Journal of Neuroscience Research, 2020 - Wiley Online Library
Brain‐derived neurotrophic factor (BDNF) is an extensively studied protein that is
evolutionarily conserved and widely distributed in the brain of vertebrates. It acts via its …

Induction of oxidative stress and apoptosis in the injured brain: Potential relevance to brain regeneration in zebrafish

SK Anand, MR Sahu, AC Mondal - Molecular Biology Reports, 2021 - Springer
Recent findings suggest a significant role of the brain-derived neurotrophic factor (BDNF) as
a mediator of brain regeneration following a stab injury in zebrafish. Since BDNF has been …

Saffron extract attenuates anxiogenic effect and improves cognitive behavior in an adult zebrafish model of traumatic brain injury

V Chaoul, M Awad, F Harb, F Najjar, A Hamade… - International Journal of …, 2022 - mdpi.com
Traumatic brain injury (TBI) has the highest mortality rates worldwide, yet effective treatment
remains unavailable. TBI causes inflammatory responses, endoplasmic reticulum stress …