In recent years, a population of unconventional T cells called 'mucosal-associated invariant
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their …

T cell lineages are defined by specialized functions and differential expression of surface
antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the …

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that recognize microbial
metabolites through a semi-invariant T cell receptor (TCR). Major questions remain …

Human leukocyte antigen (HLA)-independent, T cell–mediated targeting of cancer cells
would allow immune destruction of malignancies in all individuals. Here, we use genome …

While most studies of T lymphocytes have focused on T cells reactive to complexes of
peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do …

High-throughput single-cell RNA sequencing is a powerful technique but only generates
short reads from one end of a cDNA template, limiting the reconstruction of highly diverse …

Mucosal associated invariant T (MAIT) cells are striking in their abundance and their strict
conservation across 150 million years of mammalian evolution, implying they must fulfill …

Mucosal‐associated invariant T (MAIT) cells represent up to 10% of circulating human T
cells. They are usually defined using combinations of non‐lineage‐specific (surrogate) …

Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved T cell subset,
which reacts to most bacteria through T cell receptor (TCR)-mediated recognition of …

Studies on the biology of mucosal-associated invariant T cells (MAIT cells) in mice have
been hampered by a lack of specific reagents. Using MR1-antigen (Ag) tetramers that …