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Thirty years of saying NO: sources, fate, actions, and misfortunes of the endothelium-derived vasodilator mediator
Endothelial cells control vascular tone by releasing nitric oxide (NO) produced by
endothelial NO synthase. The activity of endothelial NO synthase is modulated by the …
endothelial NO synthase. The activity of endothelial NO synthase is modulated by the …
[HTML][HTML] PTX3, a humoral pattern recognition molecule, in innate immunity, tissue repair, and cancer
Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern
recognition molecule conserved in evolution which acts as a key component of humoral …
recognition molecule conserved in evolution which acts as a key component of humoral …
RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3-dependent macrophage homeostasis
X Han, L Liu, S Huang, W **ao, Y Gao, W Zhou… - Nature …, 2023 - nature.com
Abstract N 6-methyladenosine (m6A), the most prevalent mRNA modification, has an
important function in diverse biological processes. However, the involvement of m6A in …
important function in diverse biological processes. However, the involvement of m6A in …
Advances in pathogenesis and treatment of essential hypertension
J Ma, X Chen - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases and
the leading cause of premature death worldwide. However, the pathogenesis of the …
the leading cause of premature death worldwide. However, the pathogenesis of the …
ccf-mtDNA as a potential link between the brain and immune system in neuro-immunological disorders
Fragments of mitochondrial DNA (mtDNA) are released outside the cell and they appear to
persist in extracellular fluids as circulating, cell-free, mtDNA (ccf-mtDNA). When compared to …
persist in extracellular fluids as circulating, cell-free, mtDNA (ccf-mtDNA). When compared to …
Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32
J Yin, H Zeng, K Fan, H **e, Y Shao, Y Lu, J Zhu… - Cell Death & …, 2022 - nature.com
Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an
essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis …
essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis …
Endothelial dysfunction and inflammatory markers of vascular disease
Vascular diseases are the main reason for morbidity and mortality worldwide. As we know,
the earlier phase of vascular diseases is endothelial dysfunction in humans, the endothelial …
the earlier phase of vascular diseases is endothelial dysfunction in humans, the endothelial …
[HTML][HTML] Novel biomarkers of atherosclerotic vascular disease—Latest insights in the research field
The atherosclerotic vascular disease is a cardiovascular continuum in which the main role is
attributed to atherosclerosis, from its appearance to its associated complications. The …
attributed to atherosclerosis, from its appearance to its associated complications. The …
Effects of hesperidin in orange juice on blood and pulse pressures in mildly hypertensive individuals: a randomized controlled trial (Citrus study)
RM Valls, A Pedret, L Calderón-Pérez… - European journal of …, 2021 - Springer
Purpose To assess the sustained and acute effects, as well as the influence of sustained
consumption on the acute effects, of orange juice (OJ) with a natural hesperidin content and …
consumption on the acute effects, of orange juice (OJ) with a natural hesperidin content and …
Exploring the clinical relevance of providing increased removal of large middle molecules
Dialysis technologies have continued to advance over recent decades; however, these
advancements have not always been met with improved patient outcomes. In part, the high …
advancements have not always been met with improved patient outcomes. In part, the high …