Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine

C Xue, Q Chu, Q Zheng, S Jiang, Z Bao, Y Su… - Signal transduction and …, 2022 - nature.com
Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Recent insights into the role of immune cells in alcoholic liver disease

S Li, HY Tan, N Wang, Y Feng, X Wang… - Frontiers in …, 2019 - frontiersin.org
Accumulating clinical and experimental evidences have demonstrated that both innate and
adaptive immunity are involved in the pathogenesis of alcoholic liver disease (ALD), in …

Epigenetic Control of Translation Checkpoint and Tumor Progression via RUVBL1‐EEF1A1 Axis

M Li, L Yang, AKN Chan, SP Pokharel, Q Liu… - Advanced …, 2023 - Wiley Online Library
Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS).
However, the epigenetic networks underlying the maintenance of oncogenic signaling and …

CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma

C Zhang, J Zhao, J Zhao, B Liu, W Tang, Y Liu… - Cancer gene …, 2022 - nature.com
Long-term alcohol use is a confirmed risk factor of liver cancer tumorigenesis and
metastasis. Multiple mechanisms responsible for alcohol related tumorigenesis have been …

Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function

S Chinnapaiyan, R Dutta, J Bala, T Parira… - Scientific Reports, 2018 - nature.com
Recurrent lung infections are a common cause of morbidity and mortality in people living
with HIV and this is exacerbated in smokers even when administered combination …

Liquid liver biopsy for disease diagnosis and prognosis

DK Tsoneva, MN Ivanov… - Journal of Clinical and …, 2023 - pmc.ncbi.nlm.nih.gov
Liver diseases are a major burden worldwide, the scope of which is expected to further grow
in the upcoming years. Clinically relevant liver dysfunction-related blood markers such as …

Epitranscriptomics in the development, functions, and disorders of cancer stem cells

L Hao, J Zhang, Z Liu, X Lin, J Guo - Frontiers in Oncology, 2023 - frontiersin.org
Biomolecular modifications play an important role in the development of life, and previous
studies have investigated the role of DNA and proteins. In the last decade, with the …

Membrane receptor MerTK is a newly identified transcriptional regulator that associates to chromatin as nanoclusters during human DC differentiation

KJE Borgman, G Flórez-Grau, MA Ricci, C Manzo… - bioRxiv, 2020 - biorxiv.org
MerTK is a transmembrane receptor tyrosine kinase (RTK) mainly expressed in dendritic
cells (DCs) and macrophages where it plays an important role in immunotolerance, but also …

Principles of analytical chemistry for toxicology

J Durner, DC Watts - Regulatory toxicology, 2021 - Springer
In the first section, a historical summary of analytical chemistry is presented. In ancient
history, one function of an analytical chemist was to confirm the identity of noble metals …

Ethanol-induced modulation of GPR55 expression in human monocyte-derived dendritic cells is accompanied by H4K12 acetylation

B Castillo-Chabeco, G Figueroa, T Parira, J Napuri… - Alcohol, 2018 - Elsevier
Inflammation supports the progression of alcohol-related organ injury. Recent research
findings have linked ethanol exposure to changes in histone acetylation and deacetylation …