Copper in diseases and treatments, and copper‐based anticancer strategies

F Tisato, C Marzano, M Porchia… - Medicinal research …, 2010 - Wiley Online Library
Copper is found in all living organisms and is a crucial trace element in redox chemistry,
growth and development. It is important for the function of several enzymes and proteins …

Copper complexes as anticancer agents

C Marzano, M Pellei, F Tisato… - Anti-Cancer Agents in …, 2009 - ingentaconnect.com
Metal-based antitumor drugs play a relevant role in antiblastic chemotherapy. Cisplatin is
regarded as one of the most effective drugs, even if severe toxicities and drug resistance …

Bonding and structure trends of thiosemicarbazone derivatives of metals—an overview

TS Lobana, R Sharma, G Bawa, S Khanna - Coordination Chemistry …, 2009 - Elsevier
This review describes the coordination chemistry of thiosemicarbazones and covers all the
metals for which complexes are reported. The coordination compounds of d-block, p-block …

Interactions of copper complexes with nucleic acids

A Erxleben - Coordination Chemistry Reviews, 2018 - Elsevier
Covalent or non-covalent interactions with DNA are the basis for many potential biomedical
applications of copper complexes, ranging from DNA structural probes and footprinting …

Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu (II) complex

F Arjmand, B Mohani, S Ahmad - European journal of medicinal chemistry, 2005 - Elsevier
The ligand [C16H10O2N4S2] L has been synthesized by the condensation reaction of 2-
mercaptobenzimidazole and diethyloxalate. The ligand L was allowed to react with bis …

Oxindoles and copper complexes with oxindole-derivatives as potential pharmacological agents

G Cerchiaro, AMC Ferreira - Journal of the Brazilian Chemical Society, 2006 - SciELO Brasil
Oxindoles are endogenous compounds found in mammalian body fluids and tissues.
Particularly, isatin (1H-indole-2, 3-dione) and its derivatives have shown a variety of …

Synthesis and characterization of dinuclear macrocyclic cobalt (II), copper (II) and zinc (II) complexes derived from 2, 2, 2′, 2′-S, S [bis (bis-N, N-2 …

F Arjmand, M Aziz - European journal of medicinal chemistry, 2009 - Elsevier
New homodinuclear macrocyclic complexes of cobalt (II), copper (II) and zinc (II) were
isolated from the newly synthesized ligand 2, 2, 2′, 2′-S, S [bis (bis-N, N-2 …

Effect of terminal N-substitution in 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde thiosemicarbazones on the mode of coordination, structure, interaction with protein …

DS Raja, G Paramaguru, NSP Bhuvanesh… - Dalton …, 2011 - pubs.rsc.org
Four 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde N-substituted thiosemicarbazone ligands
(H2-OQtsc-R, where R= H, Me, Et or Ph) and their corresponding new copper (II) complexes …

Copper (II) complexes with substituted thiosemicarbazones of α-ketoglutaric acid: synthesis, X-ray structures, DNA binding studies, and nuclease and biological …

M Baldini, M Belicchi-Ferrari, F Bisceglie… - Inorganic …, 2004 - ACS Publications
New α-ketoglutaric acid thiosemicarbazone (H3ct) derivatives and their copper complexes
were synthesized and characterized by analytical and spectroscopic (IR and NMR) methods …

[HTML][HTML] Synthesis, characterization, biological studies (DNA binding, cleavage, antibacterial and topoisomerase I) and molecular docking of copper (II) benzimidazole …

F Arjmand, S Parveen, M Afzal, M Shahid - Journal of Photochemistry and …, 2012 - Elsevier
To explore the therapeutic potential of copper-based benzimidazole complexes, tetranuclear
Cu (II) complex 1 and dinuclear ternary amino acid complexes 2 and 3 {L-trp and L-val …