Theranostics, a promising modern concept combining diagnostic capabilities and
therapeutic effects, has been used for optimizing and personalizing the treatment of many …

Ongoing research on malignant and normal cell biology has substantially enhanced the
understanding of the biology of cancer and carcinogenesis. This has led to the development …

Melanoma represents the most aggressive form of skin cancer, and its incidence continues
to rise worldwide. 18 F–FDG PET imaging has transformed diagnostic nuclear medicine and …

The overexpression of peptide receptors in certain tumors as compared to endogeneous
expression levels represents the molecular basis for the design of peptide-based tools for …

Background Diabetic retinopathy is a leading cause of blindness. The objective was to
design a novel fusion protein, Tat PTD-Endostatin-RGD, to treat retinal neovascularization …

Effective targeting of α v β 3 integrin is of high relevance in cancer research as this protein is
overexpressed on several types of tumor cells, making such receptor ideal for the …

OBJECTIVE. The aim of the present study is to investigate the biologic effects of internal
irradiation and the therapeutic effectiveness of 131I-labeled arginine-glycine-aspartate …

Abstract Nonpeptidic Arg‐Gly‐Asp (RGD)‐mimic ligands were designed and synthesized by
click chemistry between an arginine–azide mimic and an aspartic acid–alkyne mimic. Some …

During tumor angiogenesis different growth factors, cytokines and other molecules interact
closely with each other to facilitate tumor cell invasion and metastatic diffusion. The most …

Fibrosis is the dramatic consequence of a dysregulated reparative process in which
activated fibroblasts (myofibroblasts) and Transforming Growth Factor β1 (TGFβ1) play a …