Inflammation in HIV and its impact on atherosclerotic cardiovascular disease

LM Obare, T Temu, SA Mallal, CN Wanjalla - Circulation research, 2024 - ahajournals.org
People living with HIV have a 1.5-to 2-fold increased risk of develo** cardiovascular
disease. Despite treatment with highly effective antiretroviral therapy, people living with HIV …

Inflammation, immune activation, and cardiovascular disease in HIV

E Nou, J Lo, SK Grinspoon - Aids, 2016 - journals.lww.com
Cardiovascular disease is one of the leading causes of morbidity and mortality in people
living with HIV. Several epidemiological studies have shown an increased risk of myocardial …

HIV-1–associated atherosclerosis: unraveling the missing link

A Kearns, J Gordon, TH Burdo, X Qin - Journal of the American College of …, 2017 - jacc.org
Cardiovascular disease, including atherosclerosis and atherosclerosis-associated
complications, is an increasing cause of morbidity and mortality in human immunodeficiency …

The importance of monocytes and macrophages in HIV pathogenesis, treatment, and cure

JH Campbell, AC Hearps, GE Martin, KC Williams… - Aids, 2014 - journals.lww.com
Monocytes and macrophages play critical roles in HIV transmission, viral spread early in
infection, and as a reservoir of virus throughout infection. There has been a recent …

Pro-inflammatory markers in relation to cardiovascular disease in HIV infection. A systematic review

AG Vos, NS Idris, RE Barth, K Klipstein-Grobusch… - PloS one, 2016 - journals.plos.org
Background In the past years many inflammatory markers have been studied in association
with clinically manifest cardiovascular disease (CVD) and carotid intima-media thickness …

Plasma IL-6 levels are independently associated with atherosclerosis and mortality in HIV-infected individuals on suppressive antiretroviral therapy

DC Hsu, YF Ma, S Hur, D Li, A Rupert, R Scherzer… - Aids, 2016 - journals.lww.com
Objective: To determine the associations of markers of immune activation with
atherosclerosis and mortality, in participants with treated and suppressed HIV infection …

Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is …

LC Ndhlovu, T Umaki, GM Chew, DC Chow… - Journal of …, 2014 - Springer
HIV-associated neurocognitive disorders (HAND) continues to be prevalent (30–50%)
despite plasma HIV-RNA suppression with combination antiretroviral therapy (cART). There …

Non-classical monocytes and monocyte chemoattractant protein-1 (MCP-1) correlate with coronary artery calcium progression in chronically HIV-1 infected adults on …

N Zungsontiporn, RR Tello, G Zhang, BI Mitchell… - PloS one, 2016 - journals.plos.org
Background Persistent inflammation and immune activation has been hypothesized to
contribute to increased prevalence of subclinical atherosclerosis and cardiovascular …