Physiological closed-loop control (PCLC) systems: Review of a modern frontier in automation
Over the past decade, there has been an unprecedented international focus on improved
quality and availability of medical care, which has reignited interest in clinical automation …
quality and availability of medical care, which has reignited interest in clinical automation …
An open source patient simulator for design and evaluation of computer based multiple drug dosing control for anesthetic and hemodynamic variables
We are witnessing a notable rise in the translational use of information technology and
control systems engineering tools in clinical practice. This paper empowers the computer …
control systems engineering tools in clinical practice. This paper empowers the computer …
Optimized PID control of depth of hypnosis in anesthesia
Abstract Background and Objective: This paper addresses the use of proportional-integral-
derivative controllers for regulating the depth of hypnosis in anesthesia by using propofol …
derivative controllers for regulating the depth of hypnosis in anesthesia by using propofol …
Enhancing wound healing through deep reinforcement learning for optimal therapeutics
Finding the optimal treatment strategy to accelerate wound healing is of utmost importance,
but it presents a formidable challenge owing to the intrinsic nonlinear nature of the process …
but it presents a formidable challenge owing to the intrinsic nonlinear nature of the process …
E-drug delivery: A futuristic approach
Highlights•E-drug delivery systems are undergoing descriptive model and technology
upgrades for patient comfort.•This technology should provide more-regulated drug dose …
upgrades for patient comfort.•This technology should provide more-regulated drug dose …
Closed-loop control of anesthesia and mean arterial pressure using reinforcement learning
General anesthesia is required for some patients in the intensive care units (ICUs) with
acute respiratory distress syndrome. Critically ill patients who are assisted by mechanical …
acute respiratory distress syndrome. Critically ill patients who are assisted by mechanical …
A comparison of propofol-to-BIS post-operative intensive care sedation by means of target controlled infusion, Bayesian-based and predictive control methods: an …
M Neckebroek, CM Ionescu, K Van Amsterdam… - Journal of Clinical …, 2019 - Springer
Purpose We evaluated the feasibility and robustness of three methods for propofol-to-
bispectral index (BIS) post-operative intensive care sedation, a manually-adapted target …
bispectral index (BIS) post-operative intensive care sedation, a manually-adapted target …
Estimating the depth of anesthesia during the induction by a novel adaptive neuro-fuzzy inference system: a case study
This study aims to estimate the depth of anesthesia (DOA) at a safe and appropriate level
taking into account the patient characteristics during the induction phase. Bi-spectral Index …
taking into account the patient characteristics during the induction phase. Bi-spectral Index …
Optimized PID control of propofol and remifentanil coadministration for general anesthesia
A closed-loop control system for the control of the depth of hypnosis in anesthesia by using
propofol-remifentanil coadministration and the Bispectral Index as feedback signal is …
propofol-remifentanil coadministration and the Bispectral Index as feedback signal is …
Linear MPC for anesthesia process with external predictor
In this paper we present a new model predictive control system for the depth of hypnosis in
general anesthesia. The depth of hypnosis is measured by the Bispectral Index Scale signal …
general anesthesia. The depth of hypnosis is measured by the Bispectral Index Scale signal …