Context Antiresorptive therapy significantly reduces fracture risk in patients with benign bone
disease and skeletal-related events (SREs) in patients with bone metastases (BM) …

Medication-related osteonecrosis of the jaw (MRONJ) is a serious side effect of bone-
modifying agents and inhibits angiogenesis agents. Although the pathogenesis of MRONJ is …

Abstract Purpose of Review Osteonecrosis of the jaw (ONJ) is a rare and severe necrotic
bone disease reflecting a compromise in the body's osseous healing mechanisms and …

Objectives To review the current evidence on the relationship between agents that affect
bone homeostasis and dental implant failures. Materials and Methods Electronic searches …

Objective This manuscript aims to provide a comprehensive review of the current knowledge
in the pathophysiology, diagnosis, prevention, and other relevant forensic and clinical …

Purpose Bisphosphonates related osteonecrosis of jaw (BRONJ) is a severe complication of
systemic BPs administration, the mechanism of which is still unclarified. Recently, platelet …

Bone metastases are dejected consequences of many types of tumors including breast,
prostate, lung, kidney, and thyroid cancers. This complicated process begins with the …

Objectives To establish osteonecrosis of the jaws in rats treated with different doses of
zoledronic acid (ZA). Methods Male Wistar rats (n= 6–7) received three consecutive weekly …

Bone is the most common site for metastasis in patients with solid tumours.
Bisphosphonates are an effective treatment for preventing skeletal related events and …

Bisphosphonates are formidable inhibitors of osteoclast-mediated bone resorption
employed for therapy of multiple myeloma (MM) subjects with osteolytic lesions …