Polygenic risk scores (PRS) estimate an individual's genetic likelihood of complex traits and
diseases by aggregating information across multiple genetic variants identified from genome …

To understand the role of environment in the pathoetiology of psychosis spectrum disorders,
research has thus far mainly investigated the effects of single exposures in isolation, such as …

Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic
disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be …

Abstract Background and Hypothesis Schizophrenia (SCZ) is associated with complex
crosstalk between the gut microbiota and host metabolism, but the underlying mechanism …

AimsPsychosis spectrum disorder has a complex pathoetiology characterised by interacting
environmental and genetic vulnerabilities. The present study aims to investigate the role of …

Importance Both adulthood stressful life events (SLEs) and liability for schizophrenia have
been associated with poor mental and physical health in the general population, but their …

Inflammation has been related to schizophrenia (SZ). The neutrophil-to-lymphocyte ratio
(NLR) is an inexpensive inflammatory marker, however, its potential predictive value in …

Little is known about genetic predisposition to relapse. Previous studies have linked
cognitive and psychopathological (mainly schizophrenia and bipolar disorder) polygenic risk …

Background Genetic and environmental factors contribute to the pathogenesis of
schizophrenia (SZ) and bipolar disorder (BD). Among genetic risk groups stratified by …

BackgroundConsistent evidence supports the involvement of genetic and environmental
factors, and their interactions, in the etiology of psychosis. First-episode psychosis (FEP) …