Application of deep learning methods in biological networks

S **, X Zeng, F **a, W Huang, X Liu - Briefings in bioinformatics, 2021 - academic.oup.com
The increase in biological data and the formation of various biomolecule interaction
databases enable us to obtain diverse biological networks. These biological networks …

Computational methods for gene regulatory networks reconstruction and analysis: a review

FM Delgado, F Gómez-Vela - Artificial intelligence in medicine, 2019 - Elsevier
In the recent years, the vast amount of genetic information generated by new-generation
approaches, have led to the need of new data handling methods. The integrative analysis of …

Integration of omic networks in a developmental atlas of maize

JW Walley, RC Sartor, Z Shen, RJ Schmitz, KJ Wu… - Science, 2016 - science.org
Coexpression networks and gene regulatory networks (GRNs) are emerging as important
tools for predicting functional roles of individual genes at a system-wide scale. To enable …

Deep learning applied to white light and narrow band imaging videolaryngoscopy: toward real‐time laryngeal cancer detection

MA Azam, C Sampieri, A Ioppi, S Africano… - The …, 2022 - Wiley Online Library
Objectives To assess a new application of artificial intelligence for real‐time detection of
laryngeal squamous cell carcinoma (LSCC) in both white light (WL) and narrow‐band …

Computational inference of gene regulatory networks: approaches, limitations and opportunities

M Banf, SY Rhee - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2017 - Elsevier
Gene regulatory networks lie at the core of cell function control. In E. coli and S. cerevisiae,
the study of gene regulatory networks has led to the discovery of regulatory mechanisms …

Network inference in systems biology: recent developments, challenges, and applications

MM Saint-Antoine, A Singh - Current opinion in biotechnology, 2020 - Elsevier
One of the most interesting, difficult, and potentially useful topics in computational biology is
the inference of gene regulatory networks (GRNs) from expression data. Although …

[HTML][HTML] Connectivity inference from neural recording data: Challenges, mathematical bases and research directions

IM de Abril, J Yoshimoto, K Doya - Neural Networks, 2018 - Elsevier
This article presents a review of computational methods for connectivity inference from
neural activity data derived from multi-electrode recordings or fluorescence imaging. We first …

Network inference with Granger causality ensembles on single-cell transcriptomics

A Deshpande, LF Chu, R Stewart, A Gitter - Cell reports, 2022 - cell.com
Cellular gene expression changes throughout a dynamic biological process, such as
differentiation. Pseudotimes estimate cells' progress along a dynamic process based on …

Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

F Liesecke, D Daudu, R Dugé de Bernonville… - Scientific reports, 2018 - nature.com
Co-expression networks are essential tools to infer biological associations between gene
products and predict gene annotation. Global networks can be analyzed at the transcriptome …

Machine learning uncovers adverse drug effects on intestinal bacteria

LE McCoubrey, M Elbadawi, M Orlu, S Gaisford… - Pharmaceutics, 2021 - mdpi.com
The human gut microbiome, composed of trillions of microorganisms, plays an essential role
in human health. Many factors shape gut microbiome composition over the life span …