Naringin: A flavanone with a multifaceted target against sepsis-associated organ injuries

B Bajgai, M Suri, H Singh, M Hanifa, JS Bhatti… - Phytomedicine, 2024 - Elsevier
Background Sepsis causes multiple organ dysfunctions and raises mortality and morbidity
rates through a dysregulated host response to infection. Despite the growing research …

Flavonoids for treating pulmonary fibrosis: present status and future prospects

A Sharma, S Wairkar - Phytotherapy Research, 2024 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with an unknown
underlying cause. There is no complete cure for IPF; however, two anti‐fibrotic agents …

Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining …

KB Okesina, AF Odetayo, WJ Adeyemi… - Laboratory animal …, 2024 - Springer
Background Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs,
including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility …

[HTML][HTML] Bitter perception and effects of foods rich in bitter compounds on human health: A comprehensive review

K Qiao, M Zhao, Y Huang, L Liang, Y Zhang - Foods, 2024 - pmc.ncbi.nlm.nih.gov
Bitter food, because of its unique taste, is not popular with the public, and is even considered
to be difficult to swallow. By binding to specific sites of bitter receptors (26 hTAS2Rs), bitter …

Hypolipidemic activity of phytochemical combinations: A mechanistic review of preclinical and clinical studies

H Nechchadi, Y Nadir, K Benhssaine, C Alem… - Food Chemistry, 2024 - Elsevier
Hyperlipidemia, a condition characterized by elevated levels of lipids in the blood, poses a
significant risk factor for various health disorders, notably cardiovascular diseases …

[HTML][HTML] Targeting Gut Microbiota with Probiotics and Phenolic Compounds in the Treatment of Atherosclerosis: A Comprehensive Review

JPR Cruz Neto, MO de Luna Freire… - Foods, 2024 - mdpi.com
Atherosclerosis (AS) is a chronic inflammatory vascular disease. Dysregulated lipid
metabolism, oxidative stress, and inflammation are the major mechanisms implicated in the …

Critical review on plant-derived quorum sensing signaling inhibitors in pseudomonas aeruginosa

K Vadakkan, K Sathishkumar, VO Mapranathukaran… - Bioorganic …, 2024 - Elsevier
Pseudomonas aeruginosa, a biofilm-forming organism with complex quorum mechanisms
(Las, Rhl, PQS, and IQS), poses an imminent danger to the healthcare sector and renders …

Naringin ameliorates liver fibrosis in zebrafish by modulating IDO1-mediated lipid metabolism and inflammatory infiltration

M Qin, J Li, Y Zheng, Y Li, Y Zhang, R Ou, W He… - Food & Function, 2023 - pubs.rsc.org
Liver fibrosis (LF) is an important reparative process in response to acute or chronic hepatic
injury, which has the potential to advance towards cirrhosis and hepatocellular carcinoma …

Regulatory mechanism and therapeutic potentials of naringin against inflammatory disorders

Y Peng, R Qu, S Xu, H Bi, D Guo - Heliyon, 2024 - cell.com
Naringin is a natural flavonoid with therapeutic properties found in citrus fruits and an active
natural product from herbal plants. Naringin has become a focus of attention in recent years …