Advancing age is a major risk factor for malignant transformation and the development of
cancer. As such, over 50% of neoplasms occur in individuals over the age of 70. The …

Malignant tumors have increased energy requirements due to growth, differentiation or
response to stress. A significant number of studies in recent years have described …

Cancer treatment continues to be a substantial problem due to tumor complexities and
persistence, demanding novel therapeutic techniques. This review investigates the …

Pancreatic cancer cells adapt to nutrient-scarce metabolic conditions by increasing their
oxidative phosphorylation reserve to survive. Here, we present a first-in-class small …

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with a high
mortality rate and relapse risk. Although progress on the genetic and molecular …

Acute Myelogenous Leukemia (AML) is a malignant disease of the hematopoietic cells,
characterized by impaired differentiation and uncontrolled clonal expansion of myeloid …

Acute myeloid leukemia (AML) is a heterogeneous group of aggressive hematological
malignancies commonly associated with treatment resistance, high risk of relapse, and …

Simple Summary A promising anti-cancer strategy is to target the tumor's dependence on
particular nutrients. However, resistance to single-agent treatment is common due to the …

Metabolic reprogramming is one of the key hallmarks in acquiring aggressive phenotype
and chemoresistance in many cancers including T-cell acute lymphoblastic leukemia (T …