Effects of selection at linked sites on patterns of genetic variability
B Charlesworth, JD Jensen - Annual review of ecology …, 2021 - annualreviews.org
Patterns of variation and evolution at a given site in a genome can be strongly influenced by
the effects of selection at genetically linked sites. In particular, the recombination rates of …
the effects of selection at genetically linked sites. In particular, the recombination rates of …
Recommendations for improving statistical inference in population genomics
The field of population genomics has grown rapidly in response to the recent advent of
affordable, large-scale sequencing technologies. As opposed to the situation during the …
affordable, large-scale sequencing technologies. As opposed to the situation during the …
Toward an evolutionarily appropriate null model: jointly inferring demography and purifying selection
The relative evolutionary roles of adaptive and non-adaptive processes remain a central
question in population genetics. Resolution of this debate has been difficult as an …
question in population genetics. Resolution of this debate has been difficult as an …
Chromosome fusion affects genetic diversity and evolutionary turnover of functional loci but consistently depends on chromosome size
Major changes in chromosome number and structure are linked to a series of evolutionary
phenomena, including intrinsic barriers to gene flow or suppression of recombination due to …
phenomena, including intrinsic barriers to gene flow or suppression of recombination due to …
The impact of purifying and background selection on the inference of population history: problems and prospects
Current procedures for inferring population history generally assume complete neutrality—
that is, they neglect both direct selection and the effects of selection on linked sites. We here …
that is, they neglect both direct selection and the effects of selection on linked sites. We here …
[PDF][PDF] How can we resolve Lewontin's paradox?
B Charlesworth, JD Jensen - Genome biology and evolution, 2022 - academic.oup.com
We discuss the genetic, demographic, and selective forces that are likely to be at play in
restricting observed levels of DNA sequence variation in natural populations to a much …
restricting observed levels of DNA sequence variation in natural populations to a much …
Evolution of a plant sex chromosome driven by expanding pericentromeric recombination suppression
DA Filatov - Scientific Reports, 2024 - nature.com
Recombination suppression around sex-determining gene (s) is a key step in evolution of
sex chromosomes, but it is not well understood how it evolves. Recently evolved sex-linked …
sex chromosomes, but it is not well understood how it evolves. Recently evolved sex-linked …
The fitness consequences of genetic divergence between polymorphic gene arrangements
B Charlesworth - Genetics, 2024 - academic.oup.com
Inversions restrict recombination when heterozygous with standard arrangements, but often
have few noticeable phenotypic effects. Nevertheless, there are several examples of …
have few noticeable phenotypic effects. Nevertheless, there are several examples of …
A butterfly pan-genome reveals that a large amount of structural variation underlies the evolution of chromatin accessibility
Despite insertions and deletions being the most common structural variants (SVs) found
across genomes, not much is known about how much these SVs vary within populations and …
across genomes, not much is known about how much these SVs vary within populations and …
Evaluating power to detect recurrent selective sweeps under increasingly realistic evolutionary null models
The detection of selective sweeps from population genomic data often relies on the premise
that the beneficial mutations in question have fixed very near the sampling time. As it has …
that the beneficial mutations in question have fixed very near the sampling time. As it has …