Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

M Kasravi, A Ahmadi, A Babajani… - Biomaterials …, 2023 - spj.science.org
Tissue-engineered decellularized extracellular matrix (ECM) scaffolds hold great potential to
address the donor shortage as well as immunologic rejection attributed to cells in …

[HTML][HTML] Decellularized extracellular matrix biomaterials for regenerative therapies: advances, challenges and clinical prospects

AA Golebiowska, JT Intravaia, VM Sathe, SG Kumbar… - Bioactive Materials, 2024 - Elsevier
Tissue engineering and regenerative medicine have shown potential in the repair and
regeneration of tissues and organs via the use of engineered biomaterials and scaffolds …

Decellularization for the retention of tissue niches

D Moffat, K Ye, S ** - Journal of tissue engineering, 2022 - journals.sagepub.com
Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Host response to biomaterials for cartilage tissue engineering: key to remodeling

F Wei, S Liu, M Chen, G Tian, K Zha, Z Yang… - … in Bioengineering and …, 2021 - frontiersin.org
Biomaterials play a core role in cartilage repair and regeneration. The success or failure of
an implanted biomaterial is largely dependent on host response following implantation. Host …

Decellularized extracellular matrix and silk fibroin-based hybrid biomaterials: A comprehensive review on fabrication techniques and tissue-specific applications

S Ghosh, F Pati - International Journal of Biological Macromolecules, 2023 - Elsevier
Biomaterials play a fundamental role in tissue engineering by providing biochemical and
physical cues that influence cellular fate and matrix development. Decellularized …

Three-dimensional bio-printing of decellularized extracellular matrix-based bio-inks for cartilage regeneration: a systematic review

M Sahranavard, S Sarkari, SM Safavi… - Biomaterials …, 2022 - pmc.ncbi.nlm.nih.gov
Cartilage injuries are common problems that increase with the population aging. Cartilage is
an avascular tissue with a relatively low level of cellular mitotic activity, which makes it …

[HTML][HTML] Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Decellularized scaffold and its elicited immune response towards the host: the underlying mechanism and means of immunomodulatory modification

J Tan, QY Zhang, LP Huang, K Huang, HQ **e - Biomaterials Science, 2021 - pubs.rsc.org
The immune response of the host towards a decellularized scaffold is complex. Not only can
a number of immune cells influence this process, but also the characteristics, preparation …

Decellularized extracellular matrix (d-ECM): the key role of the inflammatory process in pre-regeneration after implantation

J Long, Z Qin, G Chen, B Song, Z Zhang - Biomaterials Science, 2023 - pubs.rsc.org
Clinical medicine is encountering the challenge of repairing soft-tissue defects. Currently,
natural and synthetic materials have been developed as natural scaffolds. Among them, the …

[HTML][HTML] Decellularized extracellular matrix particle-based biomaterials for cartilage repair applications

P Guo, N Jiang, C Mini, G Miklosic, S Zhu… - Journal of Materials …, 2023 - Elsevier
Abstract Cartilage Decellularized ExtraCellular Matrix (dECM) materials have shown
promising cartilage regeneration capacity due to their chondrogenic bioactivity. However …