Multinuclear biologically active Ru, Rh, Os and Ir arene complexes

P Štarha - Coordination Chemistry Reviews, 2021 - Elsevier
The development of multinuclear homometallic biologically active complexes is attractive for
modern bioinorganic chemistry, because this concept offers a multiplication of the …

State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations

E Domínguez-Jurado, A Lara-Sánchez, I Bravo… - Coordination Chemistry …, 2025 - Elsevier
Cancer is a major health concern and a leading cause of death worldwide. Among all
cancer types, breast cancer has the highest incidence rate. The treatment of breast cancer …

Synthesis and structure of new binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes: investigation on antiproliferative activity and apoptosis …

MSM Kasim, S Sundar, R Rengan - Inorganic chemistry frontiers, 2018 - pubs.rsc.org
A series of binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes (1–6) of
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …

RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo

OA Lenis-Rojas, MP Robalo, AI Tomaz… - Inorganic …, 2018 - ACS Publications
Ruthenium (II) complexes are currently considered a viable alternative to the widely used
platinum complexes as efficient anticancer agents. We herein present the synthesis and …

Promoting the anticancer activity with multidentate furan-2-carboxamide functionalized aroyl thiourea chelation in binuclear half-sandwich ruthenium (II) complexes

SK Thangavel, MS Mohamed Kasim… - Inorganic …, 2024 - ACS Publications
A new set of binuclear arene ruthenium complexes [Ru2 (p-cymene) 2 (k4-N2OS)(L1-L3)
Cl2](Ru 2 L1–Ru 2 L3) encompassing furan-2-carboxamide-based aroylthiourea derivatives …

Ruthenium (II) p-cymene complexes of a benzimidazole-based ligand capable of VEGFR2 inhibition: hydrolysis, reactivity and cytotoxicity studies

S Bhattacharyya, K Purkait, A Mukherjee - Dalton Transactions, 2017 - pubs.rsc.org
The design of Ru or other metal-based anticancer agents may achieve better and faster
optimization if the ligands used are also designed to have standalone functions. In this …

Synthesis, crystal structure, cytotoxicity study, DNA/protein binding and molecular docking of dinuclear copper (II) complexes

A Bhunia, S Mistri, RK Manne, MK Santra… - Inorganica Chimica …, 2019 - Elsevier
Abstract The Schiff base 2-[(3-Methylamino-propylimino)-methyl]-phenol (HL) has been
used for the synthesis of three dinuclear Cu (II) complexes, namely [Cu 2 L 2 (dca) 2](1),[Cu …

The organic chemistry of poly (1H-pyrazol-1-yl) methanes

I Alkorta, RM Claramunt, E Diez-Barra, J Elguero… - Coordination Chemistry …, 2017 - Elsevier
Since their first synthesis by Hückel (1937) and the first systematic exploration by Trofimenko
(1970), interest in poly (1H-pyrazol-1-yl) methanes (bis, tris and tetrakis) has increased …

Dinuclear [{(p-cym) RuCl} 2 (μ-phpy)](PF 6) 2 and heterodinuclear [(ppy) 2 Ir (μ-phpy) Ru (p-cym) Cl](PF 6) 2 complexes: synthesis, structure and anticancer activity

SK Tripathy, U De, N Dehury, S Pal, HS Kim… - Dalton …, 2014 - pubs.rsc.org
Dinuclear [{( p -cym)RuCl} 2 (μ-phpy)](PF 6 ) 2 and heterodinuclear [(ppy) 2 Ir(μ-phpy)Ru( p -cym)Cl](PF
6 ) 2 complexes: synthesis, structure and ant ... - Dalton Transactions (RSC Publishing) DOI:10.1039/C4DT01033G …

Golden jubilee for scorpionates: Recent advances in organometallic chemistry and their role in catalysis

C Pettinari, R Pettinari, F Marchetti - Advances in Organometallic Chemistry, 2016 - Elsevier
This review aims to describe some recent trends in organometallic complexes containing
scorpionate ligands. Particular attention will be paid to the ligands structure, reagents, and …