Comprehensive insights into medicinal research on imidazole-based supramolecular complexes
SR Li, YM Tan, L Zhang, CH Zhou - Pharmaceutics, 2023 - mdpi.com
The electron-rich five-membered aromatic aza-heterocyclic imidazole, which contains two
nitrogen atoms, is an important functional fragment widely present in a large number of …
nitrogen atoms, is an important functional fragment widely present in a large number of …
Construction of homo and heteronuclear Ru (II), Ir (III) and Re (I) complexes for target specific cancer therapy
More than 10 million death tolls in 2020 were reported as a result of heinous impact of
cancer, making it second most prime cause of death after cardiovascular diseases. In …
cancer, making it second most prime cause of death after cardiovascular diseases. In …
Recent advances in cytotoxicity, cellular uptake and mechanism of action of ruthenium metallodrugs: A review
Due to these limitations of platinum-based drugs, it has now become a challenge for
researchers to find out a potential scaffold furnished with indispensable properties like …
researchers to find out a potential scaffold furnished with indispensable properties like …
Mitochondrial targeting half-sandwich iridium (III) and ruthenium (II) dppf complexes and in vitro anticancer assay
J Liu, Y Wu, G Yang, Z Liu, X Liu - Journal of Inorganic Biochemistry, 2023 - Elsevier
Considering the potential application of half-sandwich and ferrocenyl-containing
organometallic complexes in the area of anticancer, four half-sandwich iridium (III)(Ir III) and …
organometallic complexes in the area of anticancer, four half-sandwich iridium (III)(Ir III) and …
Mitochondria-targeted cyclometalated iridium-β-carboline complexes as potent non-small cell lung cancer therapeutic agents
Natural products and metals play a crucial role in cancer research and the development of
antitumor drugs. We designed and synthesized three new carboline-based cyclometalated …
antitumor drugs. We designed and synthesized three new carboline-based cyclometalated …
Cyclometalated Ru (II) β-carboline complexes induce cell cycle arrest and apoptosis in human HeLa cervical cancer cells via suppressing ERK and Akt signaling
Two new cyclometalated Ru (II)-β-carboline complexes,[Ru (dmb) 2 (Cl-Ph-βC)](PF6)(dmb=
4, 4′-dimethyl-2, 2′-bipyridine; Cl-Ph-βC= Cl-phenyl-9H-pyrido [3, 4-b] indole; RuβC-3) …
4, 4′-dimethyl-2, 2′-bipyridine; Cl-Ph-βC= Cl-phenyl-9H-pyrido [3, 4-b] indole; RuβC-3) …