Density functional theory, molecular docking, In vitro and In vivo anti-inflammatory investigation of lapachol isolated from Fernandoa adenophylla
Medicinal plants are the main source of active chemical constituents responsible for curing
or mitigating various ailments. To discover new, safe, and effective drug candidates the …
or mitigating various ailments. To discover new, safe, and effective drug candidates the …
The 7-Hydroxyflavone attenuates chemotherapy-induced neuropathic pain by targeting inflammatory pathway
Vincristine and paclitaxel are widely used chemotherapeutic drugs for the treatment of brain
tumors, breast cancer, leukemia, lymphomas, and malignant solid tumors. Though, these …
tumors, breast cancer, leukemia, lymphomas, and malignant solid tumors. Though, these …
Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism
A series of new thiadiazine derivatives including 2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-
3-yl) propanoic acids (a) and 4-methyl-2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-3-yl) …
3-yl) propanoic acids (a) and 4-methyl-2-(5-alkyl/aryl-6-thioxo-1, 3, 5-thiadiazinan-3-yl) …
[HTML][HTML] Cassia artemisiodes attenuates nociceptive and diabetes-induced neuropathic pain modalities apropos antioxidant and anti-inflammatory mechanisms
R Ullah, W Badshah, G Ali, A Ullah, SU Khan… - Biomedicine & …, 2022 - Elsevier
Cassia plants have a considerable position in conventional systems of medicine. The
possible anti-nociceptive, anti-inflammatory, and anti-neuropathic properties of Cassia …
possible anti-nociceptive, anti-inflammatory, and anti-neuropathic properties of Cassia …
Comparative in-vitro anti-inflammatory, anticholinesterase and antidiabetic evaluation: Computational and kinetic assessment of succinimides cyano-acetate …
This research was planned to synthesize cyano-acetate derivatives of succinimide and
evaluate its comparative biological efficacy as anti-inflammatory, anti-cholinesterase and …
evaluate its comparative biological efficacy as anti-inflammatory, anti-cholinesterase and …
Synthesizing cyclohex-2-enone derivatives and exploring their bioactivities for drug discovery
D Jiang, L Wen, F Fan - Tetrahedron Letters, 2024 - Elsevier
Cyclohex-2-enones have aroused great interest among chemists due to their wide natural
occurrence and readily accessible functionalizations. Therefore, multiple synthetic methods …
occurrence and readily accessible functionalizations. Therefore, multiple synthetic methods …
Analagesic and anti-inflammatory potentials of a less ulcerogenic thiadiazinethione derivative in animal models: biochemical and histochemical correlates
K Rahman, G Ali, R Khan, I Khan, I Ali… - Drug Design …, 2022 - Taylor & Francis
Purpose Gastric ulcer induced by NSAIDs is the major medical concern and researchers are
utilizing several approaches to combat this medical issue. In the current study, we …
utilizing several approaches to combat this medical issue. In the current study, we …
Isolation, invitro, invivo anti-inflammatory, analgesic and antioxidant potential of Habenaria plantegania Lindl
Habenaira plantaginea belong to orchid family which is native to Asia. Members of this
family are commonly famous for the cure of pain and inflammation. To date, no research was …
family are commonly famous for the cure of pain and inflammation. To date, no research was …
Mechanistic efficacy assessment of selected novel methanimine derivatives against vincristine induced Neuropathy: in-vivo, Ex-vivo and In-silico correlates
Vincristine induced peripheral neuropathy (VIPN) is a serious untoward side effect suffered
by cancer patients, which still lacks an adequate therapeutic approach. This study examined …
by cancer patients, which still lacks an adequate therapeutic approach. This study examined …
Synthesis, molecular structure and multiple biological activities of β-cycloketols using methylamine catalyst
B Anandhan, T Sumathi, P Sivakumar… - Journal of Molecular …, 2023 - Elsevier
The reaction of substituted benzaldehyde with acetylacetone in the presence of
methylamine as a catalyst leads to the formation of β-cycloketols were successfully …
methylamine as a catalyst leads to the formation of β-cycloketols were successfully …