Telomere length as a marker of biological age: state-of-the-art, open issues, and future perspectives
A Vaiserman, D Krasnienkov - Frontiers in genetics, 2021 - frontiersin.org
Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …
aging. An accelerated rate of telomere attrition is also a common feature of age-related …
Regular, intense exercise training as a healthy aging lifestyle strategy: preventing DNA damage, telomere shortening and adverse DNA methylation changes over a …
Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …
delaying the onset of age-related diseases and preventing early death. The length of …
Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …
Exercise mitigates age-related metabolic diseases by improving mitochondrial dysfunction
D Jia, Z Tian, R Wang - Ageing Research Reviews, 2023 - Elsevier
The benefits of regular physical activity are related to delaying and reversing the onset of
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …
ageing and age-related disorders, including cardiomyopathy, neurodegenerative diseases …
Exercise training increases telomerase reverse transcriptase gene expression and telomerase activity: A systematic review and meta-analysis
Telomeres protect genomic stability and shortening is one of the hallmarks of ageing.
Telomerase reverse transcriptase (TERT) is the major protein component of telomerase …
Telomerase reverse transcriptase (TERT) is the major protein component of telomerase …
[HTML][HTML] Physical activity, a modulator of aging through effects on telomere biology
Aging is a complex process that is not well understood but involves finite changes at the
genetic and epigenetic level. Physical activity is a well-documented modulator of the …
genetic and epigenetic level. Physical activity is a well-documented modulator of the …
Physical activity on telomere length as a biomarker for aging: a systematic review
M Schellnegger, AC Lin, N Hammer, LP Kamolz - Sports medicine-open, 2022 - Springer
Background Overall life expectancy continues to rise, approaching 80 years of age in
several developed countries. However, healthy life expectancy lags far behind, which has, in …
several developed countries. However, healthy life expectancy lags far behind, which has, in …
Osteocalcin and its forms respond similarly to exercise in males and females
Introduction Acute exercise increases osteocalcin (OC), a marker of bone turnover, and in
particular the undercarboxylated form (ucOC). Males and females differ in baseline levels of …
particular the undercarboxylated form (ucOC). Males and females differ in baseline levels of …
Muscle miRNAs are influenced by sex at baseline and in response to exercise
Background Sex differences in microRNA (miRNA) expression profiles have been found
across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body …
across multiple tissues. Skeletal muscle is one of the most sex-biased tissues of the body …
Expression of Telomeric Repeat–Containing RNA Decreases in Sarcopenia and Increases after Exercise and Nutrition Intervention
KV Chang, YC Chen, WT Wu, HJ Shen, KC Huang… - Nutrients, 2020 - mdpi.com
Sarcopenia is defined as aging-related loss of muscle mass and function. Telomere length
in chromosomes shortens with age and is modulated by telomeric repeat-containing RNA …
in chromosomes shortens with age and is modulated by telomeric repeat-containing RNA …