Ebselen and analogues: Pharmacological properties and synthetic strategies for their preparation
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
Synthesis of organoselenium compounds with elemental selenium
YT Ma, MC Liu, YB Zhou, HY Wu - Advanced Synthesis & …, 2021 - Wiley Online Library
In the recent decade, growing efforts have been devoted to employing elemental selenium
as a selenium source in organic synthesis. In contrast to unstable, smelly, and toxic previous …
as a selenium source in organic synthesis. In contrast to unstable, smelly, and toxic previous …
Rational design and action mechanisms of chemically innovative organoselenium in cancer therapy
Organo-seleno compounds (org-Se) have been widely used in antitumor, antiviral, and
antiinflammatory therapy; antioxidation and other biological fields. As such, they have made …
antiinflammatory therapy; antioxidation and other biological fields. As such, they have made …
Recent developments in the synthesis of biologically relevant selenium-containing scaffolds
Recent, many methods have been reported for the synthesis of selenium-containing
bioactive scaffolds because of their interesting reactivity and potential pharmaceutical …
bioactive scaffolds because of their interesting reactivity and potential pharmaceutical …
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N6-Methyladenosine-Modified RNAs
M Micaelli, A Dalle Vedove, L Cerofolini… - ACS Pharmacology & …, 2022 - ACS Publications
YTHDF proteins bind the N 6-methyladenosine (m6A)-modified mRNAs, influencing their
processing, stability, and translation. Therefore, the members of this protein family play …
processing, stability, and translation. Therefore, the members of this protein family play …
Transition-metal-free synthesis of unsymmetrical diaryl chalcogenides from arenes and diaryl dichalcogenides
A transition-metal-free synthetic method has been developed for the synthesis of
unsymmetrical diaryl chalcogenides (S, Se, and Te) from diaryl dichalcogenides and arenes …
unsymmetrical diaryl chalcogenides (S, Se, and Te) from diaryl dichalcogenides and arenes …
Recent advances in organic synthesis applying elemental selenium
T Guo, Z Li, L Bi, L Fan, P Zhang - Tetrahedron, 2022 - Elsevier
The synthesis of organoselenium compounds through C–Se bond-forming has attracted
immense attention due to their biological values and extensive pharmaceutical applications …
immense attention due to their biological values and extensive pharmaceutical applications …
Photoinduced Construction of Thieno[3,4-c]quinolin-4(5H)-ones/Selenopheno[3,4-c]quinolin-4(5H)-ones Using Diphenyl Disulfide or Diphenyl Diselenide as Sulfur …
SY Tian, JJ Ai, JH Han, W Rao, SS Shen… - The Journal of …, 2022 - ACS Publications
A photocatalytic synthesis of thieno [3, 4-c] quinolin-4 (5 H)-ones/selenopheno [3, 4-c]
quinolin-4 (5 H)-ones using diphenyl disulfide or diphenyl diselenide as sulfur or selenium …
quinolin-4 (5 H)-ones using diphenyl disulfide or diphenyl diselenide as sulfur or selenium …
KOtBu Mediated Synthesis of Phenanthridinones and Dibenzoazepinones
Synthesis of substituted phenanthridinones and dibenzoazepinones has been realized from
2-halo-benzamides in the presence of potassium tert-butoxide and a catalytic amount of 1 …
2-halo-benzamides in the presence of potassium tert-butoxide and a catalytic amount of 1 …
Multifunctional Antioxidants: Regenerable Radical‐Trap** and Hydroperoxide‐Decomposing Ebselenols
Regenerable, multifunctional ebselenol antioxidants were prepared that could quench
peroxyl radicals more efficiently than α‐tocopherol. These compounds act as better mimics …
peroxyl radicals more efficiently than α‐tocopherol. These compounds act as better mimics …