[HTML][HTML] therapeutic oligonucleotides: An outlook on chemical strategies to improve endosomal trafficking

P Mangla, Q Vicentini, A Biscans - Cells, 2023 - mdpi.com
The potential of oligonucleotide therapeutics is undeniable as more than 15 drugs have
been approved to treat various diseases in the liver, central nervous system (CNS), and …

The coming age of antisense oligos for the treatment of hepatic ischemia/reperfusion (IRI) and other liver disorders: role of oxidative stress and potential antioxidant …

S Yao, A Kasargod, R Chiu, TR Torgerson… - Antioxidants, 2024 - mdpi.com
Imbalances in the redox state of the liver arise during metabolic processes, inflammatory
injuries, and proliferative liver disorders. Acute exposure to intracellular reactive oxygen …