Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

Backscattering silicon spectrometer (BASIS): sixteen years in advanced materials characterization

NC Osti, N Jalarvo, E Mamontov - Materials Horizons, 2024 - pubs.rsc.org
Quasielastic neutron scattering (QENS) is an experimental technique that can measure
parameters of mobility, such as diffusion jump rate and jump length, as well as localized …

[HTML][HTML] A concept of a broadband inverted geometry spectrometer for the Second Target Station at the Spallation Neutron Source

E Mamontov, C Boone, MJ Frost, KW Herwig… - Review of Scientific …, 2022 - pubs.aip.org
BWAVES is an acronym for Broadband Wide-Angle VElocity Selector spectrometer,
indicating that a novel WAVES (Wide-Angle VElocity Selector) device will be used to select …

Lipid lateral diffusion: mechanisms and modulators

VK Sharma, H Srinivasan, J Gupta, S Mitra - Soft Matter, 2024 - pubs.rsc.org
The lateral diffusion of lipids within membrane is of paramount importance, serving as a
central mechanism in numerous physiological processes including cell signaling …

Free energy surface and molecular mechanism of slow structural transitions in lipid bilayers

R Punia, G Goel - Journal of Chemical Theory and Computation, 2023 - ACS Publications
Lipid membrane remodeling, crucial for many cellular processes, is governed by the
coupling of membrane structure and shape fluctuations. Given the importance of the∼ nm …

Curcumin accelerates the lateral motion of DPPC membranes

VK Sharma, J Gupta, H Srinivasan, H Bhatt… - Langmuir, 2022 - ACS Publications
Curcumin, the main ingredient in turmeric, has attracted attention due to its potential anti-
inflammatory, anticancer, wound-healing, and antioxidant properties. Though curcumin …

Modulation of Phase Behavior and Microscopic Dynamics in Cationic Vesicles by 1-Decyl-3-methylimidazolium Bromide

J Gupta, VK Sharma, H Srinivasan, H Bhatt, VG Sakai… - Langmuir, 2023 - ACS Publications
Synthetic cationic lipids have garnered significant attention as promising candidates for
gene/DNA transfection in therapeutic applications. The phase behavior of the vesicles …

Microscopic diffusion in cationic vesicles across different phases

J Gupta, VK Sharma, H Srinivasan, H Bhatt… - Physical Review …, 2022 - APS
Understanding the phase behavior and microscopic diffusion mechanism of cationic
vesicles is crucial for controlled-release kinetics in gene/DNA transfection. Here, we report …

Free energy surface and molecular characterization of slow structural transitions in lipid bilayers

R Punia, G Goel - bioRxiv, 2023 - biorxiv.org
The need to incorporate specific molecular-scale features for largescale structural changes
in biological membranes necessitate use of a multi scale computational approach. Here, this …

Broadband Wide-Angle VElocity Selector (BWAVES) neutron spectrometer designed for the SNS Second Target Station

E Mamontov, HN Bordallo, O Delaire… - EPJ Web of …, 2022 - epj-conferences.org
A recently proposed wide-angle velocity selector (WAVES) device for choosing the velocity
of detected neutrons after they have been scattered by the sample paves the way for …