The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …

The lacrimal gland is the major contributor to the aqueous layer of the tear film which
consists of water, electrolytes and proteins. The amount and composition of this layer is …

ContextPostmenopausal hormone replacement therapy (HRT) use is common in the United
States. Some research suggests that estrogen may have detrimental effects on the tear film …

This report describes the prevalence of self‐reported dry eye syndrome and associations
with systemic and ocular factors in an older Australian population. Participants of the …

PURPOSE: To present evidence establishing the relationship between inflammation and dry
eye and supporting the use of antiinflammatory therapy for dry eye. DESIGN: Analysis of …

Objective. We have recently discovered that women with primary and secondary Sjögren's
syndrome are androgen‐deficient. We hypothesize that this hormone insufficiency …

Purpose: Previous research has demonstrated that sex steroids exert a significant influence
on the structure and function of numerous ocular tissues. To begin to explore the underlying …

Homeostasis of the tear film involves delicate hormonal and neuronal regulatory
mechanisms. The eye appears to be a target organ for sex hormones, particularly the …

Dry eye syndrome (DES) refers to a spectrum of ocular surface diseases with diverse and
frequently multiple aetiologies. The common feature of the various manifestations of DES is …

The trilaminar tear film, composed of the lipid, aqueous and mucin layers, has many
functions including defending the ocular surface. The aqueous layer has several soluble …