Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond

JC Hsu, P Liu, Y Song, W Song, RJ Saladin… - Chemical Society …, 2024 - pubs.rsc.org
Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …

Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain

J Nong, PM Glassman, JW Myerson… - ACS …, 2023 - ACS Publications
Ex vivo-loaded white blood cells (WBC) can transfer cargo to pathological foci in the central
nervous system (CNS). Here we tested affinity ligand driven in vivo loading of WBC in order …

Delivery strategy to enhance the therapeutic efficacy of Liver Fibrosis via Nanoparticle Drug Delivery systems

J Liu, J Liu, W Mu, Q Ma, X Zhai, B **, Y Liu, N Zhang - ACS nano, 2024 - ACS Publications
Liver fibrosis (LF) is a pathological repair reaction caused by a chronic liver injury that affects
the health of millions of people worldwide, progressing to life-threatening cirrhosis and liver …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X **, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Designing drug delivery systems for cell therapy

LLW Wang, Y Gao, Z Feng, DJ Mooney… - Nature Reviews …, 2024 - nature.com
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …

Bio‐Responsive Sliver Peroxide‐Nanocarrier Serves as Broad‐Spectrum Metallo‐β‐lactamase Inhibitor for Combating Severe Pneumonia

H Li, S Duan, L Li, G Zhao, L Wei, B Zhang… - Advanced …, 2024 - Wiley Online Library
Abstract Metallo‐β‐lactamases (MBLs) represent a prevalent resistance mechanism in Gram‐
negative bacteria, rendering last‐line carbapenem‐related antibiotics ineffective. Here, a …

Cell–drug conjugates

Y Wang, J Shi, M **n, AR Kahkoska, J Wang… - Nature Biomedical …, 2024 - nature.com
By combining living cells with therapeutics, cell–drug conjugates can potentiate the
functions of both components, particularly for applications in drug delivery and therapy. The …

A twindrive precise delivery system of platelet-neutrophil hybrid membrane regulates macrophage combined with CD47 blocking for postoperative immunotherapy

S Sheng, L **, Y Zhang, W Sun, L Mei, D Zhu… - ACS …, 2024 - ACS Publications
During wound healing after cancer surgery, platelets, neutrophils, and macrophages
accumulate at the wound site and induce important pathophysiological features. Utilizing …