[HTML][HTML] Levetiracetam mechanisms of action: from molecules to systems

IJ Contreras-García, N Cárdenas-Rodríguez… - Pharmaceuticals, 2022 - mdpi.com
Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

Seizures and epilepsy in patients with ischaemic stroke

JP Zöllner, FC Schmitt, F Rosenow, K Kohlhase… - … research and practice, 2021 - Springer
Background With the increased efficacy of stroke treatments, diagnosis and specific
treatment needs of patients with post-stroke seizures (PSS) and post-stroke epilepsy have …

Antiepileptics topiramate and levetiracetam alleviate behavioral deficits and reduce neuropathology in APP swe/PS 1dE9 transgenic mice

JQ Shi, BR Wang, YY Tian, J Xu, L Gao… - CNS neuroscience & …, 2013 - Wiley Online Library
Background The close relationship between epileptic seizure and Alzheimer's disease (AD)
has been demonstrated in the past decade. Valproic acid, a traditional first‐line antiepileptic …

[HTML][HTML] Guidelines for the treatment of acute ischaemic stroke

MA De Leciñana, JA Egido, I Casado, M Ribó… - Neurologia (English …, 2014 - Elsevier
Abstract Introduction Update of Acute Ischaemic Stroke Treatment Guidelines of the Spanish
Neurological Society based on a critical review of the literature. Recommendations are …

[HTML][HTML] Epigenetic regulation of neuroinflammation in Alzheimer's Disease

Y Ma, W Wang, S Liu, X Qiao, Y **ng, Q Zhou, Z Zhang - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disease and
clinically manifests with cognitive decline and behavioral disabilities. Over the past years …

Non-convulsive status epilepticus after ischemic stroke: a hospital-based stroke cohort study

V Belcastro, S Vidale, G Gorgone, LR Pisani… - Journal of …, 2014 - Springer
To evaluate in the setting of a stroke unit ward the usefulness of a prolonged (> 6 h) video-
EEG recording (PVEEG) in identifying non-convulsive status epilepticus (NCSE) in patients …

[HTML][HTML] Guía para el tratamiento del infarto cerebral agudo

MA de Leciñana, JA Egido, I Casado, M Ribó… - Neurología, 2014 - Elsevier
Introducción Actualización de la guía para el tratamiento del infarto cerebral agudo de la
Sociedad Española de Neurología basada en la revisión y análisis de la bibliografía …

Levetiracetam alleviates cognitive decline in Alzheimer's disease animal model by ameliorating the dysfunction of the neuronal network

XY Zheng, HC Zhang, YD Lv, FY **, XJ Wu… - Frontiers in aging …, 2022 - frontiersin.org
Background Patients with Alzheimer's disease (AD) have a significantly higher risk of
seizures than other individuals in an age-matched population, suggesting a close …

Levetiracetam attenuates rotenone-induced toxicity: A rat model of Parkinson's disease

O Erbaş, M Yılmaz, D Taşkıran - Environmental toxicology and …, 2016 - Elsevier
Abstract Levetiracetam (LEV), a second-generation anti-epileptic drug, is used for treatment
of both focal and generalized epilepsy. Growing body of evidence suggests that LEV may …

International Post Stroke Epilepsy Research Consortium (IPSERC): a consortium to accelerate discoveries in preventing epileptogenesis after stroke

NK Mishra, J Engel, DS Liebeskind… - Epilepsy & …, 2022 - epilepsybehavior.com
Recent advances in stroke management have led to a significant reduction in stroke
mortality [1–4]; however, there has not been much progress in the prevention and treatment …