[HTML][HTML] Aging of the eye: Lessons from cataracts and age-related macular degeneration
A Cvekl, J Vijg - Ageing Research Reviews, 2024 - Elsevier
Aging is the greatest risk factor for chronic human diseases, including many eye diseases.
Geroscience aims to understand the effects of the aging process on these diseases …
Geroscience aims to understand the effects of the aging process on these diseases …
[HTML][HTML] Extracellular vesicles in degenerative retinal diseases: A new therapeutic paradigm
F Manai, A Smedowski, K Kaarniranta… - Journal of Controlled …, 2024 - Elsevier
Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/
ectosomes, have been extensively investigated in the last 20 years, although their biological …
ectosomes, have been extensively investigated in the last 20 years, although their biological …
Extracellular vesicles: an emerging player in retinal homeostasis
A Chatterjee, R Singh - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Extracellular vesicles (EVs) encompass secreted membrane vesicles of varied sizes,
including exosomes (− 30–200 nm) and microvesicles (MVs) that are∼ 100–1,000 nm in …
including exosomes (− 30–200 nm) and microvesicles (MVs) that are∼ 100–1,000 nm in …
[HTML][HTML] Pluripotent stem cell-derived models of retinal disease: Elucidating pathogenesis, evaluating novel treatments, and estimating toxicity
Blindness poses a growing global challenge, with approximately 26% of cases attributed to
degenerative retinal diseases. While gene therapy, optogenetic tools, photosensitive …
degenerative retinal diseases. While gene therapy, optogenetic tools, photosensitive …
Simultaneous profiling of RNA isoforms and chromatin accessibility of single cells of human retinal organoids
S Zhang, Y ** the complement
and innate immune systems in check. It is unclear whether the reduced sialylation seen …
and innate immune systems in check. It is unclear whether the reduced sialylation seen …