Aging is the greatest risk factor for chronic human diseases, including many eye diseases.
Geroscience aims to understand the effects of the aging process on these diseases …

Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/
ectosomes, have been extensively investigated in the last 20 years, although their biological …

Extracellular vesicles (EVs) encompass secreted membrane vesicles of varied sizes,
including exosomes (− 30–200 nm) and microvesicles (MVs) that are∼ 100–1,000 nm in …

Blindness poses a growing global challenge, with approximately 26% of cases attributed to
degenerative retinal diseases. While gene therapy, optogenetic tools, photosensitive …

Single-cell multi-omics sequencing is a powerful approach to analyze complex mechanisms
underlying neuronal development and regeneration. However, current methods lack the …

The seminal role of autophagy during age-related macular degeneration (AMD) lies in the
clearance of a number of reactive oxidative species that generate dysfunctional …

The retinal pigment epithelium (RPE) between retinal photoreceptors and choroidal
capillaries is a single layer of cells that are of critical importance to the eye. RPE cells are …

Age-related macular degeneration (AMD), the leading cause of central vision loss in the
elderly, involves death of the retinal pigment epithelium (RPE) and light-sensing …

Platelet-rich plasma (PRP), a blood product containing high concentrations of platelets, has
been increasingly used for the treatment of a number of diseases because of its anti …

Purpose To perform a review of research, funding, and clinical translation efforts for
extracellular vesicles (EVs) within vision science. Design Retrospective analysis of …