Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance

Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

[HTML][HTML] Molecular mechanisms of platinum‑based chemotherapy resistance in ovarian cancer

L Yang, HJ **e, YY Li, X Wang, XX Liu… - Oncology …, 2022 - spandidos-publications.com
Cisplatin is one of the most effective chemotherapy drugs for ovarian cancer, but resistance
is common. The initial response to platinum‑based chemotherapy is as high as 80%, but in …

Astaxanthin activated the Nrf2/HO-1 pathway to enhance autophagy and inhibit ferroptosis, ameliorating acetaminophen-induced liver injury

X Cai, S Hua, J Deng, Z Du, D Zhang… - … Applied Materials & …, 2022 - ACS Publications
Acetaminophen (APAP)-induced liver injury (AILI) is a common liver disease in clinical
practice. Only one clinically approved drug, N-acetylcysteine (NAC), for the treatment of AILI …

Challenges and recent progress in oral drug delivery systems for biopharmaceuticals

B Homayun, X Lin, HJ Choi - Pharmaceutics, 2019 - mdpi.com
Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

[HTML][HTML] Mesoporous silica nanoparticles for therapeutic/diagnostic applications

S Jafari, H Derakhshankhah, L Alaei, A Fattahi… - Biomedicine & …, 2019 - Elsevier
Based on unique intrinsic properties of mesoporous silica nanoparticles (MSNs) such as
high surface area, large pore size, good biocompatibility and biodegradability, stable …

[HTML][HTML] Mesoporous silica nanoparticles for drug and gene delivery

Y Zhou, G Quan, Q Wu, X Zhang, B Niu, B Wu… - … pharmaceutica sinica B, 2018 - Elsevier
Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential
biomedical applications. With tailored mesoporous structure, huge surface area and pore …

Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

[HTML][HTML] Sol–gel based materials for biomedical applications

GJ Owens, RK Singh, F Foroutan, M Alqaysi… - Progress in materials …, 2016 - Elsevier
Sol–gel chemistry offers a flexible approach to obtaining a diverse range of materials. It
allows differing chemistries to be achieved as well as offering the ability to produce a wide …

Dynamic light scattering and transmission electron microscopy in drug delivery: a roadmap for correct characterization of nanoparticles and interpretation of results

SK Filippov, R Khusnutdinov, A Murmiliuk, W Inam… - Materials …, 2023 - pubs.rsc.org
In this focus article, we provide a scrutinizing analysis of transmission electron microscopy
(TEM) and dynamic light scattering (DLS) as the two common methods to study the sizes of …