[HTML][HTML] Obesity, male infertility, and the sperm epigenome

JR Craig, TG Jenkins, DT Carrell, JM Hotaling - Fertility and sterility, 2017 - Elsevier
Obesity is a growing epidemic and a common problem among reproductive-age men that
can both cause and exacerbate male-factor infertility by means of endocrine abnormalities …

An overview of the heterogeneity of major depressive disorder: current knowledge and future prospective

KV Athira, S Bandopadhyay… - Current …, 2020 - benthamdirect.com
Major depressive disorder (MDD) is estimated to impose maximum debilitating effects on the
society by 2030, with its critical effects on health, functioning, quality of life and concomitant …

Maternal prenatal depression predicts infant negative affect via maternal inflammatory cytokine levels

HC Gustafsson, EL Sullivan, EK Nousen… - Brain, behavior, and …, 2018 - Elsevier
Maternal depressive symptoms during pregnancy are associated with risk for offspring
emotional and behavioral problems, but the mechanisms by which this association occurs …

Multigenerational and transgenerational effects of paternal exposure to drugs of abuse on behavioral and neural function

LR Goldberg, TJ Gould - European Journal of Neuroscience, 2019 - Wiley Online Library
Addictions are highly heritable disorders, with heritability estimates ranging from 39% to
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …

Evaluation of maternal inflammation as a marker of future offspring ADHD symptoms: A prospective investigation

HC Gustafsson, EL Sullivan, EAJ Battison… - Brain, behavior, and …, 2020 - Elsevier
Early life predictors of attention-deficit/hyperactivity disorder (ADHD) are critically needed;
they could inform etiological theory and may help identify new prevention targets. The …

Transgenerational epigenetics: Integrating soma to germline communication with gametic inheritance

A Sharma - Mechanisms of Ageing and Development, 2017 - Elsevier
Evidence supporting germline mediated epigenetic inheritance of environmentally induced
traits has increasingly emerged over the past several years. Although the mechanisms …

[HTML][HTML] Metabolic features and regulation of the healing cycle—A new model for chronic disease pathogenesis and treatment

RK Naviaux - Mitochondrion, 2019 - Elsevier
Without healing, multicellular life on Earth would not exist. Without healing, one injury
predisposes to another, leading to disability, chronic disease, accelerated aging, and death …

Understanding the epigenetic basis of sex differences in depression

GE Hodes, DM Walker, B Labonté… - Journal of …, 2017 - Wiley Online Library
Epigenetics refers to potentially heritable processes that can mediate both lasting and
transient changes in gene expression in the absence of genome sequence alterations. The …

Prenatal programming of stress responsiveness and behaviours: Progress and perspectives

H Hamada, SG Matthews - Journal of Neuroendocrinology, 2019 - Wiley Online Library
Parental exposure to stress or glucocorticoids either before or during pregnancy can have
profound influences on neurodevelopment, neuroendocrine function and behaviours in …

The link among microbiota, epigenetics, and disease development

A El-Sayed, L Aleya, M Kamel - Environmental Science and Pollution …, 2021 - Springer
The microbiome is a community of various microorganisms that inhabit or live on the skin of
humans/animals, sharing the body space with their hosts. It is a sort of complex ecosystem of …