Interneuron types as attractors and controllers

G Fishell, A Kepecs - Annual review of neuroscience, 2020 - annualreviews.org
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Inhibitory stabilization and cortical computation

S Sadeh, C Clopath - Nature Reviews Neuroscience, 2021 - nature.com
Neuronal networks with strong recurrent connectivity provide the brain with a powerful
means to perform complex computational tasks. However, high-gain excitatory networks are …

AgeAnno: a knowledgebase of single-cell annotation of aging in human

K Huang, H Gong, J Guan, L Zhang, C Hu… - Nucleic acids …, 2023 - academic.oup.com
Aging is a complex process that accompanied by molecular and cellular alterations. The
identification of tissue-/cell type-specific biomarkers of aging and elucidation of the detailed …

Sensory processing deficits and related cortical pathological changes in Alzheimer's disease

NK Zhang, SK Zhang, LI Zhang, HW Tao… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily affecting
cognitive functions. However, sensory deficits in AD start to draw attention due to their high …

Exciting complexity: the role of motor circuit elements in ALS pathophysiology

ZI Gunes, VWY Kan, XQ Ye, S Liebscher - Frontiers in neuroscience, 2020 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is a fatal disease, characterized by the degeneration of
both upper and lower motor neurons. Despite decades of research, we still to date lack a …

[HTML][HTML] Inhibition in the auditory cortex

F Studer, TR Barkat - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The auditory system provides us with extremely rich and precise information about the
outside world. Once a sound reaches our ears, the acoustic information it carries travels from …

Hearing loss and brain plasticity: the hyperactivity phenomenon

B Herrmann, BE Butler - Brain Structure and Function, 2021 - Springer
Many aging adults experience some form of hearing problems that may arise from auditory
peripheral damage. However, it has been increasingly acknowledged that hearing loss is …

Cortical microcircuit mechanisms of mismatch negativity and its underlying subcomponents

JM Ross, JP Hamm - Frontiers in Neural Circuits, 2020 - frontiersin.org
In the neocortex, neuronal processing of sensory events is significantly influenced by
context. For instance, responses in sensory cortices are suppressed to repetitive or …

Cerebellum-specific deletion of the GABAA receptor δ subunit leads to sex-specific disruption of behavior

S Rudolph, C Guo, SL Pashkovski, T Osorno, WF Gillis… - Cell Reports, 2020 - cell.com
Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABA A subunit-
containing GABA A receptors (δGABA A Rs) that respond to ambient GABA levels and …

Hearing in complex environments: auditory gain control, attention, and hearing loss

BD Auerbach, HJ Gritton - Frontiers in neuroscience, 2022 - frontiersin.org
Listening in noisy or complex sound environments is difficult for individuals with normal
hearing and can be a debilitating impairment for those with hearing loss. Extracting …