HMGB1 in health and disease

R Kang, R Chen, Q Zhang, W Hou, S Wu, L Cao… - Molecular aspects of …, 2014 - Elsevier
Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

The role of inflammation in immune system of diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications

T Yue, Y Shi, S Luo, J Weng, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy is one of the most common complications of diabetes mellitus and the
leading cause of low vision and blindness worldwide. Mounting evidence demonstrates that …

Diabetic retinopathy: vascular and inflammatory disease

F Semeraro, A Cancarini, R dell'Omo… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetic retinopathy (DR) is the leading cause of visual impairment in the working‐age
population of the Western world. The pathogenesis of DR is complex and several vascular …

Endothelial dysfunction in diabetic retinopathy

F Gui, Z You, S Fu, H Wu, Y Zhang - Frontiers in Endocrinology, 2020 - frontiersin.org
Diabetic retinopathy (DR) is a diabetic complication which affects retinal function and results
in severe loss of vision and relevant retinal diseases. Retinal vascular dysfunction caused …

[PDF][PDF] Inflammatory and angiogenic biomarkers in diabetic retinopathy

S Kaštelan, I Orešković, F Bišćan, H Kaštelan… - Biochemia …, 2020 - hrcak.srce.hr
Review Page 1 Abstract Diabetic retinopathy (DR) is one of the most common microvascular
complications of diabetes mellitus (DM) and a leading cause of blindness in working-age …

Novel approaches for treating diabetic retinopathy based on recent pathogenic evidence

R Simo, C Hernandez - Progress in Retinal and eye Research, 2015 - Elsevier
Diabetic retinopathy remains as a leading cause of blindness in developed countries.
Current treatments target late stages of DR when vision has already been significantly …

Local and systemic inflammatory biomarkers of diabetic retinopathy: an integrative approach

S Vujosevic, R Simó - Investigative ophthalmology & visual …, 2017 - iovs.arvojournals.org
Purpose: To review the usefulness of local and systemic inflammatory biomarkers of diabetic
retinopathy (DR) to implement a more personalized treatment. Methods: An integrated …

Changes in aqueous and vitreous inflammatory cytokine levels in proliferative diabetic retinopathy: a systematic review and meta-analysis

RH Mason, SA Minaker, G Lahaie Luna, P Bapat… - Eye, 2022 - nature.com
Background Diabetic retinopathy is a major complication of diabetes mellitus, where in its
most advanced form ischemic changes lead to the development of retinal …

[HTML][HTML] Neurovascular unit: a new target for treating early stages of diabetic retinopathy

R Simó, O Simó-Servat, P Bogdanov, C Hernández - Pharmaceutics, 2021 - mdpi.com
The concept of diabetic retinopathy as a microvascular disease has evolved and is now
considered a more complex diabetic complication in which neurovascular unit impairment …

Dexamethasone intravitreal implant in the treatment of diabetic macular edema

PU Dugel, F Bandello, A Loewenstein - Clinical Ophthalmology, 2015 - Taylor & Francis
Diabetic macular edema (DME) resembles a chronic, low-grade inflammatory reaction, and
is characterized by blood–retinal barrier (BRB) breakdown and retinal capillary leakage …