The continued threat of emerging flaviviruses

TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Integrated control strategies for dengue, Zika, and Chikungunya virus infections

N Côrtes, A Lira, W Prates-Syed, J Dinis Silva… - Frontiers in …, 2023 - frontiersin.org
Arboviruses are a major threat to public health in tropical regions, encompassing over 534
distinct species, with 134 capable of causing diseases in humans. These viruses are …

Zika virus infection enhances future risk of severe dengue disease

LC Katzelnick, C Narvaez, S Arguello… - Science, 2020 - science.org
The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …

[HTML][HTML] Dengue and Zika virus diagnostic testing for patients with a clinically compatible illness and risk for infection with both viruses

TM Sharp - MMWR. Recommendations and Reports, 2019 - cdc.gov
Dengue and Zika viruses are closely related mosquitoborne flaviviruses with similar
transmission cycles, distribution throughout the tropics and subtropics, and disease …

Impact of preexisting dengue immunity on Zika virus emergence in a dengue endemic region

I Rodriguez-Barraquer, F Costa, EJM Nascimento… - Science, 2019 - science.org
The clinical outcomes associated with Zika virus (ZIKV) in the Americas have been well
documented, but other aspects of the pandemic, such as attack rates and risk factors, are …

Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics

RA Aogo, JV Zambrana, N Sanchez, S Ojeda… - Science translational …, 2023 - science.org
Sequential infection with multiple dengue virus (DENV) serotypes is thought to induce
enduring protection against dengue disease. However, long-term antibody waning has been …

Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction

SB Biering, DL Akey, MP Wong, WC Brown, NTN Lo… - Science, 2021 - science.org
Medically important flaviviruses cause diverse disease pathologies and collectively are
responsible for a major global disease burden. A contributing factor to pathogenesis is …

Prior dengue virus infection and risk of Zika: A pediatric cohort in Nicaragua

A Gordon, L Gresh, S Ojeda, LC Katzelnick… - PLoS …, 2019 - journals.plos.org
Background Zika virus (ZIKV) emerged in northeast Brazil in 2015 and spread rapidly across
the Americas, in populations that have been largely exposed to dengue virus (DENV). The …

Influence of previous Zika virus infection on acute dengue episode

CF Estofolete, AF Versiani, FS Dourado… - PLoS neglected …, 2023 - journals.plos.org
Background The co-circulation of flaviviruses in tropical regions has led to the hypothesis
that immunity generated by a previous dengue infection could promote severe disease …

The association between Zika virus infection and microcephaly in Brazil 2015–2017: An observational analysis of over 4 million births

OJ Brady, A Osgood-Zimmerman, NJ Kassebaum… - PLoS …, 2019 - journals.plos.org
Background In 2015, high rates of microcephaly were reported in Northeast Brazil following
the first South American Zika virus (ZIKV) outbreak. Reported microcephaly rates in other …