The reactivation of a stored memory in the brain can make the memory transiently labile.
During the time it takes for the memory to restabilize (reconsolidate) the memory can either …

Fear memory is the best-studied form of memory. It was thoroughly investigated in the past
60 years mostly using two classical conditioning procedures (contextual fear conditioning …

The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and
memory. Here we begin with an overview of the LC-NE system. We then consider how both …

The pharmacological research on the Cannabis sativa-derived compounds has never
terminated. Among the phytocannabinoids without psychotropic effects, the prevalent one in …

Learning to associate cues or contexts with potential threats or rewards is adaptive and
enhances survival. Both aversive and appetitive memories are therefore powerful drivers of …

Post-traumatic stress disorder (PTSD), characterized by abnormally persistent and
distressing memories, is a chronic debilitating condition in need of new treatment options …

Abstract Purpose of Review Anxiety-and trauma-related disorders are prevalent and
debilitating mental illnesses associated with a significant socioeconomic burden. Current …

Post-traumatic stress disorder (PTSD) is characterized by poor adaptation to a traumatic
experience. This disorder affects approximately 10% of people at some point in life. Current …

The most important discoveries in pharmacology, such as certain classes of analgesics or
chemotherapeutics, started from natural extracts which have been found to have effects in …

Ayahuasca ingestion modulates brain activity, neurotransmission, gene expression and
epigenetic regulation. N, N-Dimethyltryptamine (DMT, one of the alkaloids in Ayahuasca) …