Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

Whole-genome duplication (WGD) events have shaped the history of many evolutionary
lineages. One such duplication has been implicated in the evolution of teleost fishes, by far …

Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

The whole-genome duplication 80 million years ago of the common ancestor of salmonids
(salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique …

The analysis of the first plant genomes provided unexpected evidence for genome
duplication events in species that had previously been considered as true diploids on the …

Marine stickleback fish have colonized and adapted to thousands of streams and lakes
formed since the last ice age, providing an exceptional opportunity to characterize genomic …

Eukaryotic cytosine methylation represses transcription but also occurs in the bodies of
active genes, and the extent of methylation biology conservation is unclear. We quantified …

We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the
chicken is a modern descendant of the dinosaurs and the first non-mammalian amniote to …

Vertebrate evolution has been shaped by several rounds of whole-genome duplications
(WGDs) that are often suggested to be associated with adaptive radiations and evolutionary …