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Evolution of biofilm-forming pathogenic bacteria in the presence of nanoparticles and antibiotic: Adaptation phenomena and cross-resistance
Background Treatment of bacterial biofilms are difficult and in many cases, expensive.
Bacterial biofilms are naturally more resilient to antimicrobial agents than their free-living …
Bacterial biofilms are naturally more resilient to antimicrobial agents than their free-living …
Enhanced antibacterial activity of repurposed mitomycin C and imipenem in combination with the lytic phage vB_KpnM-VAC13 against clinical isolates of Klebsiella …
Klebsiella pneumoniae is an opportunistic Gram-negative pathogen that employs different
strategies (resistance and persistence) to counteract antibiotic treatments. This study aimed …
strategies (resistance and persistence) to counteract antibiotic treatments. This study aimed …
Antibiotic tolerance is associated with a broad and complex transcriptional response in E. coli
Antibiotic treatment kills a large portion of a population, while a small, tolerant subpopulation
survives. Tolerant bacteria disrupt antibiotic efficacy and increase the likelihood that a …
survives. Tolerant bacteria disrupt antibiotic efficacy and increase the likelihood that a …
Real-time monitoring of Pseudomonas aeruginosa biofilm growth dynamics and persister cells' eradication
M Žiemytė, M Carda-Diéguez… - Emerging Microbes & …, 2021 - Taylor & Francis
Biofilm formation and the appearance of persister cells with low metabolic rates are key
factors affecting conventional treatment failure and antibiotic resistance. Using impedance …
factors affecting conventional treatment failure and antibiotic resistance. Using impedance …
[HTML][HTML] A quantitative survey of bacterial persistence in the presence of antibiotics: towards antipersister antimicrobial discovery
Background: Bacterial persistence to antibiotics relates to the phenotypic ability to survive
lethal concentrations of otherwise bactericidal antibiotics. The quantitative nature of the time …
lethal concentrations of otherwise bactericidal antibiotics. The quantitative nature of the time …
[HTML][HTML] Rethinking dormancy: Antibiotic persisters are metabolically active, non-growing cells
KMT Rahman, R Amaratunga, XY Butzin… - International Journal of …, 2025 - Elsevier
Objectives Bacterial persisters are a subpopulation of multidrug-tolerant cells capable of
surviving and resuming activity after exposure to bactericidal antibiotic concentrations …
surviving and resuming activity after exposure to bactericidal antibiotic concentrations …
Mechanisms for Rapid Evolution of Carbapenem Resistance in a Clinical Isolate of Pseudomonas aeruginosa
C Xu, D Wang, X Zhang, H Liu, G Zhu, T Wang… - Frontiers in …, 2020 - frontiersin.org
Infections by Pseudomonas aeruginosa are difficult to cure due to its high intrinsic and
acquired antibiotic resistance. Once colonized the human host, and thanks to antibiotic …
acquired antibiotic resistance. Once colonized the human host, and thanks to antibiotic …
An isogenic E. coli population gives rise to multiple persister phenotypes
Bacterial persisters are a multidrug-tolerant subpopulation capable of surviving and
resuscitating after lethal antibiotic treatment, leading to relapsing infections and the …
resuscitating after lethal antibiotic treatment, leading to relapsing infections and the …
Vibrio splendidus persister cells induced by host coelomic fluids show a similar phenotype to antibiotic‐induced counterparts
Y Li, TK Wood, W Zhang, C Li - Environmental microbiology, 2021 - Wiley Online Library
Persister cells are dormant variants of regular cells that are multidrug tolerant and have
heterogeneous phenotypes; these cells are a potential threat to hosts because they can …
heterogeneous phenotypes; these cells are a potential threat to hosts because they can …
Identification of a Toxin–Antitoxin System That Contributes to Persister Formation by Reducing NAD in Pseudomonas aeruginosa
J Zhou, S Li, H Li, Y **, F Bai, Z Cheng, W Wu - Microorganisms, 2021 - mdpi.com
Bacterial persisters are slow-growing or dormant cells that are highly tolerant to bactericidal
antibiotics and contribute to recalcitrant and chronic infections. Toxin/antitoxin (TA) systems …
antibiotics and contribute to recalcitrant and chronic infections. Toxin/antitoxin (TA) systems …