ω-3 and ω-6 polyunsaturated fatty acids, obesity and cancer

S D'Angelo, ML Motti, R Meccariello - Nutrients, 2020 - mdpi.com
Recently, nutraceutical bioactive compounds in foods have been discovered for their
potential health benefits regarding the prevention of chronic disorders, such as cancer, and …

Changes in lipids composition and metabolism in colorectal cancer: a review

A Pakiet, J Kobiela, P Stepnowski, T Sledzinski… - Lipids in health and …, 2019 - Springer
Altered metabolism of lipids is currently considered a hallmark characteristic of many
malignancies, including colorectal cancer (CRC). Lipids are a large group of metabolites …

[HTML][HTML] Tissue invasion and metastasis: Molecular, biological and clinical perspectives

WG Jiang, AJ Sanders, M Katoh, H Ungefroren… - Seminars in cancer …, 2015 - Elsevier
Cancer is a key health issue across the world, causing substantial patient morbidity and
mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to …

Targeting ferroptosis in breast cancer

Z Li, L Chen, C Chen, Y Zhou, D Hu, J Yang, Y Chen… - Biomarker …, 2020 - Springer
Ferroptosis is a recently discovered distinct type of regulated cell death caused by the
accumulation of lipid-based ROS. Metabolism and expression of specific genes affect the …

Omega-3 fatty acids and cancer cell cytotoxicity: implications for multi-targeted cancer therapy

D D'Eliseo, F Velotti - Journal of clinical medicine, 2016 - mdpi.com
Cancer is a major disease worldwide. Despite progress in cancer therapy, conventional
cytotoxic therapies lead to unsatisfactory long-term survival, mainly related to development …

Vitamin E, antioxidant and nothing more

MG Traber, J Atkinson - Free radical biology and medicine, 2007 - Elsevier
All of the naturally occurring vitamin E forms, as well as those of synthetic all-rac-α-
tocopherol, have relatively similar antioxidant properties, so why does the body prefer α …

The opposing effects of n− 3 and n− 6 fatty acids

G Schmitz, J Ecker - Progress in lipid research, 2008 - Elsevier
Polyunsaturated fatty acids (PUFAs) can be classified in n− 3 fatty acids and n− 6 fatty acids,
and in westernized diet the predominant dietary PUFAs are n− 6 fatty acids. Both types of …

The involvement of polyunsaturated fatty acids in apoptosis mechanisms and their implications in cancer

M Montecillo-Aguado, B Tirado-Rodriguez… - International Journal of …, 2023 - mdpi.com
Cancer is a significant global public health issue and, despite advancements in detection
and treatment, the prognosis remains poor. Cancer is a complex disease characterized by …

Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease

JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers

R Mallick, S Basak, AK Duttaroy - Progress in lipid research, 2021 - Elsevier
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …