Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

[HTML][HTML] Progress in the application of sustained-release drug microspheres in tissue engineering

L Ruan, M Su, X Qin, Q Ruan, W Lang, M Wu, Y Chen… - Materials Today Bio, 2022 - Elsevier
Sustained-release drug-loaded microspheres provide a long-acting sustained release, with
targeted and other effects. There are many types of sustained-release drug microspheres …

Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture

K Moshksayan, N Kashaninejad, ME Warkiani… - Sensors and Actuators B …, 2018 - Elsevier
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …

Microfluidic trends in drug screening and drug delivery

J Feng, J Neuzil, A Manz, C Iliescu, P Neuzil - TrAC Trends in Analytical …, 2023 - Elsevier
The low probability of a drug candidate's clinical success, the time consumed and the high
cost of bringing a drug from concept to market emphasizes the need for new approaches to …

Using spheroids as building blocks towards 3D bioprinting of tumor microenvironment

P Zhuang, YH Chiang, MS Fernanda… - International journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Cancer still ranks as a leading cause of mortality worldwide. Although considerable efforts
have been dedicated to anticancer therapeutics, progress is still slow, partially due to the …

Biopolymer microparticles prepared by microfluidics for biomedical applications

YK Jo, D Lee - Small, 2020 - Wiley Online Library
Biopolymers are macromolecules that are derived from natural sources and have attractive
properties for a plethora of biomedical applications due to their biocompatibility …

Cell-laden microfluidic microgels for tissue regeneration

W Jiang, M Li, Z Chen, KW Leong - Lab on a Chip, 2016 - pubs.rsc.org
Regeneration of diseased tissue is one of the foremost concerns for millions of patients who
suffer from tissue damage each year. Local delivery of cell-laden hydrogels offers an …

Advances of microfluidics in biomedical engineering

Q Zhong, H Ding, B Gao, Z He… - Advanced materials …, 2019 - Wiley Online Library
As an enabling technique, microfluidic systems have developed rapidly in recent years to
emerge as a powerful tool in the field of biomedical engineering. Microfluidics enables …

Imaging technologies for microfluidic biochips

J Han, U Kang, EY Moon, H Yoo, B Gweon - BioChip Journal, 2022 - Springer
With the growing interest in biochips, numerous efforts have been made to recapitulate a
more reliable and physiologically relevant environment within chips, resulting in significant …

Spheroid construction strategies and application in 3D bioprinting

C Lu, C Gao, H Qiao, Y Zhang, H Liu, A **… - Bio-Design and …, 2024 - Springer
Tissue engineering has been striving toward designing and producing natural and
functional human tissues. Cells are the fundamental building blocks of tissues. Compared …